Basicity, Water Solubility and Intrinsic Viscosity of Carboxymethyl Chitosan as a Biofunctional Material

Abstract

The basicity, water solubility, intrinsic viscosity and molecular weight of carboxymethyl chitosan (CM-chitosan) were investigated. The solution pH remained at about 9.2 at the concentration of higher than 2.0 g/L. The isoelectric point of CM-chitosan was about 4.5 of pH, and the solubility of CM-chitosan at the solution pH of 2.0 to 6.0 was lower than 5 g/L. The acetic acid could be replaced by hydrochloric acid as solvent for the viscosity-average molecular weight determination of chitosan. The intrinsic viscosity values of CM-chitosan have significant differences in acidic and alkaline conditions. The viscosity-average molecular weight of CM-chitosan was (3.8 ± 0.2) × 105, consistent with that of product chitosan of blank test.

Evaluation of a Spinosad Controlled-Release Formulation Based on Chitosan Carrier: Insecticidal Activity against Plutella xylostella (L.) Larvae and Dissipation Behavior in Soil

“…Commercially available 3% SEW was supplied by Hunan Nongda Haite Agricultural Chemical Co., Ltd. (Hunan, China). Chitosan with a viscosity-average molecular weight of (5.2 ± 0.4) × 10 5 and a degree of deacetylation larger than 90% was obtained from Lan-Ji Biotechnology Development Co., Ltd. (Shanghai, China) . Dispersants WELL-301 and WELL-303 were provided by Nanping Well Biochemical Scientific and Technological Co., Ltd. (Fujian, China).…”

Antibacterial Polyelectrolytic chitosan derivatives conjugated natural rubber latex films with minimized bacterial adhesion

“…Chitosan solution was prepared in 0.2 M CH 3 COOH/0.1 M CH 3 COONa and the viscosity measurements were done using Ubbelohde viscometer at 25 ± 1 C, where "K" and "a" are 6.59 × 10 −5 ml/g and 0.88 respectively. For the Mv determination of CMCS 0.10 mol/L NaCl were used as solvent at 25 C. [24,25] where K and a values are 7.92 × 10 −5 ml/g and 1.00 respectively.…”

Synthesis and wound healing performance of new water‐soluble chitosan derivatives

“…In addition to hybrid polymer technique, chemical modifications of CS have been explored by the studies focused on various fields such as enhanced solubility, 13,14 controlled drug release, 15 wound healing, 16–21 cell adhesion, 22,23 antibacterial applications, 24 antioxidant properties, 25 and improved carrier for gene therapy 26 . During the modifications, CS was subjected to various chemical transformations including etherification, esterification, and graft copolymerization 27 .…”

“…Inspiring by the unique ability of CS to combine with a wide range of water-soluble natural or synthetic polymers, a number of remarkable studies, particularly in pharmaceutical field, have focused on the synthesis of the enhanced hybrid CS derivatives. [9][10][11][12] In addition to hybrid polymer technique, chemical modifications of CS have been explored by the studies focused on various fields such as enhanced solubility, 13,14 controlled drug release, 15 wound healing, [16][17][18][19][20][21] cell adhesion, 22,23 antibacterial applications, 24 antioxidant properties, 25 and improved carrier for gene therapy. 26 During the modifications, CS was subjected to various chemical transformations including etherification, esterification, and graft copolymerization.…”