Basilar Impression and Platybasia in Paget's Disease

Poppel, Maxwell H.; Jacobson, Harold G.; Duff, Bedford K.; Gottlieb, Charles

doi:10.1148/61.4.639

Cited by 34 publications

(6 citation statements)

References 6 publications

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“…In our study, we measured the BA along the center of pituitary fossa. McGregor, 8 Poppel, 9 Konigsberg, 21 and Brailsford 22 also evaluated BA similarly in their studies (►Table 4). Botelho et al 7 reported that the diagnosis of platybasia should be made when BA is above 133 degrees.…”

Section: Discussionmentioning

confidence: 99%

Computed Tomography Evaluation of Craniovertebral Junction in Asymptomatic Central Rural Indian Population

Gupta

Dhok

Shaikh

et al. 2020

JNRP

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Objectives Craniovertebral junction (CVJ) is a unique, mobile and complicated component of our spine which necessitates specific study pertaining to its structure as well as pathologies. This study aims to report the normative data detailing the CVJ anatomy among the rural population of Central India which would help us in understanding the joint dynamics. Materials and Methods A retrospective observational study was undertaken in the Department of Neurosurgery and Radiology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Maharashtra, from December 2018 to May 2019. A total of 255 head injury patients with a normal CT brain cervical spine were included in this study. Anterior and posterior atlantodental interval (AADI/PADI), clivus length (CL), foramen magnum diameter (FMD), Boogard’s and basal angle (BOO & BA) were measured and analyzed. Statistical Analysis Statistical analysis was done using Microsoft Excel 2016. A web-based, open source application known as OpenEpi.com (version 3.01) was used for applying unpaired t-test. Results This study had a mean age of 42.9 years. The difference in mean value of AADI between male and female population was not found to be statistically significant, while in case of PADI, CL, FMD, BOO and BA, it was found to be significant (p < 0.05). On comparison of cases with age ≤ 20 years and > 20 years, we found the difference in values of ADI, CL and FMD to be statistically significant (p < 0.05). Conclusion Although there are some similarities, namely, AADI measurements as compared with other studies, there are differences in cutoff values of other parameters. Being a major draining reference center for rural population in India, this data can be extrapolated to a similar population for reference.

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Section: Discussionmentioning

confidence: 99%

Computed Tomography Evaluation of Craniovertebral Junction in Asymptomatic Central Rural Indian Population

Gupta

Dhok

Shaikh

et al. 2020

JNRP

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“…In the controls in the present study the mean was 0.7 Ϯ 3.3 mm. Closest to this latter measure is the one reported by Poppel and coworkers, 19 which was based on 102 predominantly male persons with a mean Chamberlain measure of 0.1 Ϯ 3.3 mm.…”

Section: Cranial Base Structure In Healthy Populationsmentioning

confidence: 91%

Skull base abnormalities in osteogenesis imperfecta: a cephalometric evaluation of 54 patients and 108 control volunteers

Kovero

Pynnönen²,

Kuurila-Svahn³

et al. 2006

JNS

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“…Common nonneoplastic complications include osseous weakening (resulting in deformity, bowing, and fractures), arthritis, and neurologic abnormalities (57)(58)(59)(60)(61)(62)(63)(64)(65). Miscellaneous entities such as osteomyelitis, extramedullary hematopoiesis, recrudescence of the lytic phase of the disease, and transference of Paget disease to a new osseous site following surgical placement of bone graft material harvested from pagetic areas are also rare, reported nonneoplastic complications (4,66,68).…”

Section: Nonneoplastic Complications Of Paget Diseasementioning

confidence: 99%

“…The major complications in the spinal column include spinal stenosis and foraminal en-croachment (secondary to osseous expansion of the vertebral bodies), fractures of the spine, basilar invagination, and spinal cord hypoxia (57)(58)(59)61). The major complications in the spinal column include spinal stenosis and foraminal en-croachment (secondary to osseous expansion of the vertebral bodies), fractures of the spine, basilar invagination, and spinal cord hypoxia (57)(58)(59)61).…”

Section: Neurologic Abnormalitiesmentioning

confidence: 99%

From the Archives of the AFIP

Smith¹,

Murphey²,

Motamedi³

et al. 2002

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Paget disease of bone is a common disorder affecting approximately 3%-4% of the population over 40 years of age. The pathologic abnormality in Paget disease is excessive and abnormal remodeling of bone. Three pathologic phases have been described: the lytic phase (incipient-active), in which osteoclasts predominate; the mixed phase (active), in which osteoblasts cause repair superimposed on the resorption; and the blastic phase (late-inactive) in which osteoblasts predominate. Radiographic appearance of Paget disease reflects these pathologic changes and is often characteristic. Initially, there is osteolysis, particularly affecting the skull (osteoporosis circumscripta) and subchondral long bones, with subsequent development of trabecular and cortical thickening and enlargement of bone in the mixed phase of the disease. Finally, areas of sclerosis may develop in the blastic phase. Frequent sites of involvement include the skull (25%-65% of cases), spine (30%-75%), pelvis (30%-75%), and proximal long bones (25%-30%). Bone scintigraphy typically demonstrates marked increased uptake of radionuclide in all phases of Paget disease. Computed tomography and magnetic resonance imaging often show changes similar to those seen radiographically in noncomplicated Paget disease with maintenance of yellow marrow. Complications of Paget disease include the effects of osseous weakening (deformity and fracture), arthritis, neurologic symptoms, and neoplastic involvement. Sarcomatous transformation is the most feared complication, occurring in approximately 1% of cases, and is seen on images as focal bone destruction extending through the cortex with an associated soft-tissue mass. Recognition of the radiologic spectrum of the appearances of Paget disease usually allows prospective diagnosis and differentiation of its associated complications, which helps guide therapy and improve patient management.

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Basilar Impression and Platybasia in Paget's Disease

Cited by 34 publications

References 6 publications

Computed Tomography Evaluation of Craniovertebral Junction in Asymptomatic Central Rural Indian Population

Computed Tomography Evaluation of Craniovertebral Junction in Asymptomatic Central Rural Indian Population

Skull base abnormalities in osteogenesis imperfecta: a cephalometric evaluation of 54 patients and 108 control volunteers

From the Archives of the AFIP

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