2023
DOI: 10.1073/pnas.2315824120
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Batteryless implantable device with built-in mechanical clock for automated and precisely timed drug administration

Min Ji Kim,
Cho Rim Kim,
Chan Soon Park
et al.

Abstract: Adherence to medication plays a crucial role in the effective management of chronic diseases. However, patients often miss their scheduled drug administrations, resulting in suboptimal disease control. Therefore, we propose an implantable device enabled with automated and precisely timed drug administration. Our device incorporates a built-in mechanical clock movement to utilize a clockwork mechanism, i.e., a periodic turn of the hour axis, enabling automatic drug infusion at precise 12-h intervals. The actuat… Show more

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