Although seemingly disparate, high-energy nuclear physics (HENP) and machine learning (ML) have begun to merge in the last few years, yielding interesting results. It is worthy to raise the profile of utilizing this novel mindset from ML in HENP, to help interested readers see the breadth of activities around this intersection. The aim of this mini-review is to inform the community of the current status and present an overview of the application of ML to HENP. From different aspects and using examples, we examine how scientific questions involving HENP can be answered using ML.