2024
DOI: 10.1177/13524585241230440
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BCG vaccination and multiple sclerosis risk: A Norwegian cohort study

Ola Nakken,
Jan Harald Aarseth,
Stig Wergeland
et al.

Abstract: Introduction: Bacillus Calmette–Guérin (BCG) vaccination induces long-lasting effects on the adaptive and innate immune systems and prevents development of experimental autoimmune encephalomyelitis and possibly also inflammatory disease activity in multiple sclerosis (MS). Objective: The objective is to examine if BCG given in early adulthood decreases MS risk. Methods: From 791,369 (52% females) Norwegians participating in a national tuberculosis screening program from 1963 to 1975, we collected information o… Show more

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