BDNF Modulation by microRNAs: An Update on the Experimental Evidence
Gilmara Gomes De Assis,
Eugenia Murawska-Ciałowicz
Abstract:MicroRNAs can interfere with protein function by suppressing their messenger RNA translation or the synthesis of its related factors. The function of brain-derived neurotrophic factor (BDNF) is essential to the proper formation and function of the nervous system and is seen to be regulated by many microRNAs. However, understanding how microRNAs influence BDNF actions within cells requires a wider comprehension of their integrative regulatory mechanisms. Aim: In this literature review, we have synthesized the e… Show more
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