“…Honey is composed of “sugars” ( Kamal and Klein, 2011 ), “disaccharides,” “water,” “proteins” ( Moreira et al, 2007 ; Won et al, 2009 ; Sak-Bosnar and Sakač, 2012 ), “amino acids” ( Hermosí;n et al, 2003 ; Iglesias et al, 2006 ), “vitamins” ( Bonté and Desmoulière, 2013 ), “minerals” ( Alqarni et al, 2014 ), “organic acids,” “phenolic compounds” ( Andersen and Markham, 2005 ), and “solid particles” ( Castro-Vázquez et al, 2007 ) as well as “volatile compounds” ( Da Silva et al, 2016 ). Honey is used as a remedy in traditional medicine to cure gastritis, snake-bite, cold, myalgia, eye infection, teething in child, dark spots, skin, diarrhea, expectorant, migraine, allergy, burns, wounds in the stomach, spleen, toothache, mouth, influenza, hypertension, atherosclerosis, diabetes mellitus, Alzheimer’s disease, cancer, urinary system, throat pain, asthma, acidity obesity, cough, and tonsils ( Mahawar and Jaroli, 2006 ; Padmanabhan and Sujana, 2008 ; Dixit et al, 2010 ; Jaroli et al, 2010 ; Oliveira et al, 2010 ; Abbasi et al, 2011 ; Benítez, 2011 ; Deb and Haque, 2011 ; Lohani, 2011b ; Yirga et al, 2011 ; Barros et al, 2012 ; Erejuwa et al, 2012 ; Haileselasie, 2012 ; Chinlampianga et al, 2013 ; Betlloch Mas et al, 201 7; Mootoosamy and Mahomoodally, 2014 ; Sreekeesoon and Mahomoodally, 2014 ; Vallejo and González, 2014 ; Vijayakumar et al, 2015b ; Waykar and Alqadhi, 2016 ; Yeshi et al, 2017 ; Altaf et al, 2018 ; Altaf and Umair, 2020 ). Honey is also utilized in nano-medicine to cure various ailments and acts as anti-apoptosis, anti-proliferative ( Oršolić, 2009 ; Li et al, 2010 ; Mandal and Mandal, 2011 ; Vallianou et al, 2014 ), anti-diabetic, antioxidant ( Omotayo et al, 2010 ; Erejuwa, 2014 ; Bobiş et al, 2018 ), antibiotic, anti-cataract, anti-inflammatory, antifungal and endophthalmitis ( Rhone and Basu, 2008 ; Vit and Jacob, 2008 ; Cernak et al, 2012 ; Salehi et al, 2014 ...…”