Begleitstoffgehalte alkoholischer Getr�nke

Aliphatic alcohols in spirits inhibit phagocytosis by human monocytes

“…Therefore, even when large volumes of these types of alcoholic beverages are consumed, the blood AA concentrations would be below the levels required to inhibit phagocytosis 11 . However, much higher amounts of AAs have been detected in distilled spirits 4,43,[44][45][46][47][48][49] . Previous studies have shown that legally produced spirits such as ''Kirschwasser'' (German cherry spirit) and Scotch whiskey contained, respectively, 37.…”

“…The concentration of AAs in different types of alcoholic drinks varies considerably [11][12][13][44][45][46][47][48][49] . Beer has been found to include up to 0.18 mM (isobutanol -1.3 g/hl) and 0.59 mM (isoamyl alcohol -5.2 g/hl) while red wine has been found to contain up to 0.63 mM (isobutanol -4.7 g/hl) and 3.25 mM (methanol -10.4 g/hl) 45 .…”

Commentary: Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response

“…However, we believe that the results published by Ng et al are not only of clinical but also of public health relevance. Short chain alcohols, also known aliphatic alcohols (AAs), including methanol and higher alcohols containing more than two carbon atoms such as 1-and 2-propanol, 1-and 2-butanol, isobutanol, and isoamyl alcohol are found in many legally and illegally produced alcoholic beverages, including beer, wine, and spirits (5)(6)(7)(8)(9)(10)(11)(12). Very large portion of the population is potentially exposed to these substances, with the latest available data from the World Health Organization, from 2016, reporting that 2.34 billion people worldwide consume alcoholic beverages, with a global annual average adult per capita alcohol consumption from legal and illegal sources was 4.7 and 1.6 l, respectively (13).…”

“…Therefore, toxicologists and public health researchers have expressed concern about potential health risks associated with consumption of alcoholic beverages containing AAs (5)(6)(7)(8)(9)(10). Although AAs are present in all types of alcoholic beverages, their concentration is typically higher in distilled spirits than in beer and wine (6,12).…”

Isopropyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

“…Metabolites of alcohol are important markers for previous alcohol consumption, see: Joya et al (2012); Helander et al (2012). For investigation of the short-chain alkyl alcohol content in alcoholic beverages, see: Lachenmeier & Musshoff (2004). For the relevance of short-chain alkyl alcohol glucuronides as alcohol markers, see; Sticht & Kä ferstein (1999).…”