Behavior and the catecholamine system of the brain in two generations of the descendants of male rats with chronic alcohol intoxication

Veretinskaya, A. G.; Vekshina, N. L.; Stanishevskaya, A. V.; Shamakina, I. Yu.; Tomilin, V. A.; Николаева, В.В.; Anokhina, I. P.; Kuznetsova, M. N.

doi:10.1134/s1819712413010091

Cited by 3 publications

(3 citation statements)

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“…5(B), but good recoveries from 95.6 to 105.7% were obtained, indicating that the proposed HPLC-CL method is applicable for the quantification of monoamine neurotransmitters in rat brain. The contents (mean ± SD) of NE, DA and 5-HT in rat brain were 0.60 ± 0.02, 0.67 ± 0.03 and 0.48 ± 0.03 ng/mg, which agree well with the reported data (Tsunoda and Funatsu, 2012;Zhu et al, 2011;Veretinskaya et al, 2013).…”

Section: Application To the Detection Of Monoamine Neurotransmitters supporting

confidence: 91%

“…It was reported that catecholamines were usually extracted by adsorption onto alumina because of attraction of the hydroxyl groups of catechol nucleus (Goldstein et al, 1981;Yi and Brown, 1991). The contents (mean ± SD) of NE, DA and 5-HT in rat brain were 0.60 ± 0.02, 0.67 ± 0.03 and 0.48 ± 0.03 ng/mg, which agree well with the reported data (Tsunoda and Funatsu, 2012;Zhu et al, 2011;Veretinskaya et al, 2013). The recoveries from alumina adsorption of NE, EP and DA were 55, 63 and 61%, respectively.…”

Section: Application To the Detection Of Monoamine Neurotransmitters supporting

confidence: 89%

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Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO₆)₂]⁵⁻–luminol chemiluminescence detection

et al. 2016

Biomedical Chromatography

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Based on the enhancing effects of norepinephrine (NE), epinephrine (EP), dopamine (DA) and 5-hydroxytryptamine (5-HT) on the chemiluminescence (CL) reaction between [Ag(HIO6 )2 ](5-) and luminol in alkaline solution, a high-performance liquid chromatography (HPLC) method with CL detection was explored for the sensitive determination of monoamine neurotransmitters for the first time. The UV-visible absorption spectra were recorded to study the enhancement mechanism of monoamine neurotransmitters on the CL of [Ag(HIO6 )2 ](5-) and luminol reaction. The HPLC separation of NE, EP, DA and 5-HT was achieved with isocratic elution using a mixture of aqueous 0.2% phosphoric acid and methanol (5:95, v/v) within 11.0 min. Under the optimized conditions, the detection limits of NE, EP, DA, and 5-HT were 4.8, 0.9, 1.9 and 2.3 ng/mL, respectively, corresponding to 17.6-96.0 pg for 20 μL sample injection. The recoveries of monoamine neurotransmitters in rat brain were >95.6% with the precisions expressed by RSD <5.0%. The validated HPLC-CL method was successfully applied for the quantification of NE, EP, DA and 5-HT in rat brain. This method has promising potential for some biological and clinical investigations focusing on the levels of monoamine neurotransmitters. Copyright © 2016 John Wiley & Sons, Ltd.

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Section: Application To the Detection Of Monoamine Neurotransmitters supporting

confidence: 91%

Section: Application To the Detection Of Monoamine Neurotransmitters supporting

confidence: 89%

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO₆)₂]⁵⁻–luminol chemiluminescence detection

et al. 2016

Biomedical Chromatography

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“…The concentrations (mean ± SD) of NE and DA measured with the proposed HPLC‐CL method were 0.55 ± 0.03 and 0.69 ± 0.07 ng/mg tissue (rat brain, n = 3). These values agree with the reported data (Tagliamonte et al ., ; Finn et al ., ; Veretinskaya et al ., ). Therefore, the present study provides a new method for the detection of CAs in rat brain.…”

Section: Resultsmentioning

confidence: 97%

Simultaneous quantification of catecholamines in rat brain by high‐performance liquid chromatography with on‐line gold nanoparticle‐catalyzed luminol chemiluminescence detection

Zhang

et al. 2014

Biomedical Chromatography

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A new method based on high-performance liquid chromatography (HPLC) coupled with on-line gold nanoparticle-catalyzed luminol chemiluminescence (CL) detection was developed for the simultaneous quantitation of catecholamines in rat brain. In the present CL system, gold nanoparticles were produced by the on-line reaction of H2 O2 , NaHCO3 -Na2 CO3 (buffer solution of luminol) and HAuCl4. Norepinephrine (NE), epinephrine (EP) and dopamine (DA) could strongly enhance the CL signal of the on-line gold nanoparticle-catalyzed luminol system. The UV-visible absorption spectra and transmission electron microscopy studies were carried out, and the CL enhancement mechanism was proposed. Catecholamines promoted the on-line formation of more gold nanoparticles, which better catalyzed the luminol-H2 O2 CL reaction. The good separation of NE, EP and DA was achieved with isocratic elution using a mixture of methanol and 0.2% aqueous phosphoric acid (5:95, v/v) within 8.5 min. Under the optimized conditions, the detection limits, defined as a signal-to-noise ratio of 3, were in the range of 1.32-1.90 ng/mL, corresponding to 26.4-38.0 pg for 20 μL sample injection. The recoveries of catecholamines added to rat brain sample were >94.6%, with the precisions <5.5%. The validated HPLC-CL method was successfully applied to determine NE and DA in rat brain without prior sample purification.

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Mapping the past, present and future research landscape of paternal effects

et al. 2020

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Background Although in all sexually reproducing organisms an individual has a mother and a father, non-genetic inheritance has been predominantly studied in mothers. Paternal effects have been far less frequently studied, until recently. In the last 5 years, research on environmentally induced paternal effects has grown rapidly in the number of publications and diversity of topics. Here, we provide an overview of this field using synthesis of evidence (systematic map) and influence (bibliometric analyses). Results We find that motivations for studies into paternal effects are diverse. For example, from the ecological and evolutionary perspective, paternal effects are of interest as facilitators of response to environmental change and mediators of extended heredity. Medical researchers track how paternal pre-fertilization exposures to factors, such as diet or trauma, influence offspring health. Toxicologists look at the effects of toxins. We compare how these three research guilds design experiments in relation to objects of their studies: fathers, mothers and offspring. We highlight examples of research gaps, which, in turn, lead to future avenues of research. Conclusions The literature on paternal effects is large and disparate. Our study helps in fostering connections between areas of knowledge that develop in parallel, but which could benefit from the lateral transfer of concepts and methods.

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Behavior and the catecholamine system of the brain in two generations of the descendants of male rats with chronic alcohol intoxication

Cited by 3 publications

References 7 publications

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO₆)₂]⁵⁻–luminol chemiluminescence detection

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO₆)₂]⁵⁻–luminol chemiluminescence detection

Simultaneous quantification of catecholamines in rat brain by high‐performance liquid chromatography with on‐line gold nanoparticle‐catalyzed luminol chemiluminescence detection

Mapping the past, present and future research landscape of paternal effects

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Behavior and the catecholamine system of the brain in two generations of the descendants of male rats with chronic alcohol intoxication

Cited by 3 publications

References 7 publications

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO6)2]5−–luminol chemiluminescence detection

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO6)2]5−–luminol chemiluminescence detection

Simultaneous quantification of catecholamines in rat brain by high‐performance liquid chromatography with on‐line gold nanoparticle‐catalyzed luminol chemiluminescence detection

Mapping the past, present and future research landscape of paternal effects

Contact Info

Product

Resources

About

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO₆)₂]⁵⁻–luminol chemiluminescence detection

Sensitive determination of norepinephrine, epinephrine, dopamine and 5‐hydroxytryptamine by coupling HPLC with [Ag(HIO₆)₂]⁵⁻–luminol chemiluminescence detection