Behavioral Effect of Terahertz Waves in C57BL/6 Mice

Miao, Qi; Liu, Rong; Li, Bing; Wang, Shuai; Fan, Runze; Zhao, Xinyi; Xu, Dehui

doi:10.3390/bios12020079

Cited by 10 publications

(6 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, this study found that terahertz radiation at 0.138 THz and 2 mW promotes synaptic transmission in the hippocampal CA1 region. At the in vivo level, Miao et al increased terahertz radiation power to 90 mW and observed that 0.14 THz radiation reduces anxiety and depression symptoms in mice while enhancing their social behavior [ 65 ]. Some studies have also used backward wave oscillators and quantum cascade lasers as terahertz sources, but these investigations are often limited to the cellular level.…”

Section: Methods For Terahertz Radiation Regulation Of Neuronsmentioning

confidence: 99%

“…Previous research has indicated that terahertz radiation can impact the morphology and functionality of neurons, and these effects are related to factors such as terahertz frequency, duration, and power [ 64 , 65 , 66 ]. Therefore, to further select appropriate terahertz radiation protocols, it is essential to analyze the distribution of research subjects and terahertz radiation protocols in the relevant literature.…”

Section: Methods For Terahertz Radiation Regulation Of Neuronsmentioning

confidence: 99%

See 1 more Smart Citation

Terahertz Radiation Modulates Neuronal Morphology and Dynamics Properties

Ma,

Ding,

Zhou

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

Terahertz radiation falls within the spectrum of hydrogen bonding, molecular rotation, and vibration, as well as van der Waals forces, indicating that many biological macromolecules exhibit a strong absorption and resonance in this frequency band. Research has shown that the terahertz radiation of specific frequencies and energies can mediate changes in cellular morphology and function by exciting nonlinear resonance effects in proteins. However, current studies have mainly focused on the cellular level and lack systematic studies on multiple levels. Moreover, the mechanism and law of interaction between terahertz radiation and neurons are still unclear. Therefore, this paper analyzes the mechanisms by which terahertz radiation modulates the nervous system, and it analyzes and discusses the methods by which terahertz radiation modulates neurons. In addition, this paper reviews the laws of terahertz radiation’s influence on neuronal morphology and kinetic properties and discusses them in detail in terms of terahertz radiation frequency, energy, and time. In the future, the safety of the terahertz radiation system should be considered first to construct the safety criterion of terahertz modulation, and the spatial resolution of the terahertz radiation system should be improved. In addition, the systematic improvement of the laws and mechanisms of terahertz modulation of the nervous system on multiple levels is the key to applying terahertz waves to neuroscience. This paper can provide a platform for researchers to understand the mechanism of the terahertz–nervous system interaction, its current status, and future research directions.

show abstract

Section: Methods For Terahertz Radiation Regulation Of Neuronsmentioning

confidence: 99%

Section: Methods For Terahertz Radiation Regulation Of Neuronsmentioning

confidence: 99%

Terahertz Radiation Modulates Neuronal Morphology and Dynamics Properties

Ma,

Ding,

Zhou

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

show abstract

“…Terahertz (THz) EMR is typically used in security screening, astronomy, tumor imaging, and biomedicine. Further, a recent in vivo study suggested that THz radiation increased antidepression, anti-anxiety, and social interactions in exposed mice [ 64 ]. Moreover, THz EMR has been reported to cause death of human primary and malignant cells [ 65 ].…”

Section: Biological Effects Of Microwavesmentioning

confidence: 99%

Microwave Radiation and the Brain: Mechanisms, Current Status, and Future Prospects

Mumtaz

Rana

Choi

et al. 2022

IJMS

View full text Add to dashboard Cite

Modern humanity wades daily through various radiations, resulting in frequent exposure and causing potentially important biological effects. Among them, the brain is the organ most sensitive to electromagnetic radiation (EMR) exposure. Despite numerous correlated studies, critical unknowns surround the different parameters used, including operational frequency, power density (i.e., energy dose), and irradiation time that could permit reproducibility and comparability between analyses. Furthermore, the interactions of EMR with biological systems and its precise mechanisms remain poorly characterized. In this review, recent approaches examining the effects of microwave radiations on the brain, specifically learning and memory capabilities, as well as the mechanisms of brain dysfunction with exposure as reported in the literature, are analyzed and interpreted to provide prospective views for future research directed at this important and novel medical technology for developing preventive and therapeutic strategies on brain degeneration caused by microwave radiation. Additionally, the interactions of microwaves with biological systems and possible mechanisms are presented in this review. Treatment with natural products and safe techniques to reduce harm to organs have become essential components of daily life, and some promising techniques to treat cancers and their radioprotective effects are summarized as well. This review can serve as a platform for researchers to understand the mechanism and interactions of microwave radiation with biological systems, the present scenario, and prospects for future studies on the effect of microwaves on the brain.

show abstract

“…Recent studies have found that THz irradiation can change the behavioral phenotype of mice to a certain extent; however, the effect of terahertz irradiation on neural stem cells in mice has not been studied. 35 Therefore, we first investigated the effects of THz irradiation on mNSCs, and we further selected hNSCs derived from iPSCs to investigate the biological effects of THz irradiation. In this study, flow cytometry was used to analyze proliferation and apoptosis in neural stem cells, and immunofluorescence was used to analyze DNA damage in neural stem cells.…”

Section: Introductionmentioning

confidence: 99%