Belief can Move Mountains

Ernst, E.

doi:10.1177/0163278704273086

Cited by 4 publications

(3 citation statements)

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“…The use of CAM is frequently not communicated to the doctor (25.5% in our survey), which is consistent with the literature. Likewise, the doctors often do not ask for additional CAM therapies, neglecting the treatment preferences of the patients (21, 22). Patients often do not know that CAM therapies are not strictly regulated by the administrations (Food and Drug Administration for the USA, Bundesinstitut für Arzneimittel und Medizinprodukte for Germany), and many of the offered substances are classified as dietary supplements and not as drugs (23).…”

Section: Discussionmentioning

confidence: 99%

Use of Complementary and Alternative Medicine in Patients Suffering from Primary Headache Disorders

et al. 2009

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Complementary and alternative medicine (CAM) is increasingly common in the treatment of primary headache disorders despite lack of evidence for efficacy in most modalities. A systematic questionnaire-based survey of CAM therapy was conducted in 432 patients who attended seven tertiary headache out-patient clinics in Germany and Austria. Use of CAM was reported by the majority (81.7%) of patients. Most frequently used CAM treatments were acupuncture (58.3%), massage (46.1%) and relaxation techniques (42.4%). Use was motivated by 'to leave nothing undone' (63.7%) and 'to be active against the disease' (55.6%). Compared with non-users, CAM users were of higher age, showed a longer duration of disease, a higher percentage of chronification, less intensity of headache, were more satisfied with conventional prophylaxis and showed greater willingness to gather information about headaches. There were no differences with respect to gender, headache diagnoses, headache-specific disability, education, income, religious attitudes or satisfaction with conventional attack therapy. A higher number of headache days, longer duration of headache treatment, higher personal costs, and use of CAM for other diseases predicted a higher number of used CAM treatments. This study confirms that CAM is widely used among primary headache patients, mostly in combination with standard care.

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Section: Discussionmentioning

confidence: 99%

Use of Complementary and Alternative Medicine in Patients Suffering from Primary Headache Disorders

et al. 2009

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“…9 Others have similarly reported the influence of patient belief on RCT outcomes. 10 Thus, we now examine inactive (control) effect sizes, comparing sham effect sizes in VS trials to placebo effect sizes in RLS drug trials. In addition, we will examine the influence of trial design (parallel versus CO designs) on control effect sizes and discuss the ramifications of these findings for RLS sleep studies.…”

Section: Rationalementioning

confidence: 99%

Sleep improvement for restless legs syndrome patients. Part IV: meta-analysis comparison of effect sizes of vibratory stimulation sham pads and placebo pills

Segawa¹,

Burbank²

2014

JPRLS

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Purpose: To determine whether sham pads used as controls in randomized clinical trials of vibratory stimulation to treat patients with sleep loss associated with restless legs syndrome perform differently than placebo pills used in comparable restless legs syndrome drug trials. Patients and methods: Sham pad effect sizes from 66 control patients in two randomized clinical trials of vibratory stimulation were compared with placebo responses from 1,024 control patients in 12 randomized clinical drug trials reporting subjective sleep measurement scales. Control patient responses were measured as the standardized difference in means corrected for correlation between beginning and ending scores and for small sample sizes. Results: For parallel randomized clinical trials, sham effects in vibratory stimulation trials were not significantly different from placebo effects in drug trials (0.37 and 0.31, respectively, Q between subgroups =0.25, P Q $0.62). Placebo effect sizes were significantly smaller in crossover drug trials than sham effect sizes in parallel vibratory stimulation trials (0.07 versus 0.37, respectively, Q between subgroups =4.59, P Q #0.03) and placebo effect sizes in parallel drug trials (0.07 versus 0.31, respectively, Q between subgroups =5.50, P Q #0.02). Conclusion: For subjective sleep loss assessments in parallel trials, sham pads in vibratory stimulation trials performed similarly to placebo pills in drug trials. Trial design (parallel versus crossover) had a large influence on control effect sizes. Placebo pills in crossover drug trials had significantly smaller effect sizes than sham pads in parallel vibratory stimulation trials or placebo pills in parallel drug trials.

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“…we do not know whether patients were aware that they may get sham or placebo acupressure, or one group got seed acupressure and the other not. The trial is labelled as double‐blind, but the possibility of unmasking patients cannot be ruled out without appropriate testing 6 …”

Section: Commentarymentioning

confidence: 99%

Auricular seed acupressure as a possible complementary option for primary dysmenorrhoea

2009

Focus on Alt & Comp Therapy

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Belief can Move Mountains

Cited by 4 publications

References 0 publications

Use of Complementary and Alternative Medicine in Patients Suffering from Primary Headache Disorders

Use of Complementary and Alternative Medicine in Patients Suffering from Primary Headache Disorders

Sleep improvement for restless legs syndrome patients. Part IV: meta-analysis comparison of effect sizes of vibratory stimulation sham pads and placebo pills

Auricular seed acupressure as a possible complementary option for primary dysmenorrhoea

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