Nowadays, the residential sector of Kazakhstan accounts for about 30% of the total energy consumption. Therefore, it is essential to analyze the energy estimation model for residential buildings in Kazakhstan so as to reduce energy consumption. This research is aimed to develop the Overall Thermal Transfer Value (OTTV) based Building Energy Simulation Model (BESM) for the reduction of energy consumption through the envelope of residential buildings in seven cities of Kazakhstan. A brute force optimization method was adopted to obtain the optimal envelope configuration varying window-to-wall ratio (WWR), the angle of a pitched roof, the depth of the overhang shading system, the thermal conductivity, and the thicknesses of wall composition materials. In addition, orientation-related analyses of the optimized cases were conducted. Finally, the economic evaluation of the base and optimized cases were presented. The results showed that an average energy reduction for heating was 6156.8 kWh, while for cooling it was almost 1912.17 kWh. The heating and cooling energy savings were 16.59% and 16.69%, respectively. The frontage of the building model directed towards the south in the cold season and north in the hot season demonstrated around 21% and 32% of energy reduction, respectively. The energy cost savings varied between 9657 to 119,221 ₸ for heating, 9622 to 36,088 ₸ for cooling.