Benchmarking Study of Cymbopogon citratus and C. nardus for Its Development of Functional Food Ingredient for Anti-diabetic Treatment

Widiputri, Diah Indriani; Gunawan-Puteri, Maria Dpt; Kartawiria, Irvan S.

doi:10.33555/iconiet.v2i2.20

Cited by 4 publications

(4 citation statements)

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“…C. nardus is indicated to be efficient in maintaining blood glucose levels despite a lack of details on its mode of action (Widiputri et al, 2019). Studies have revealed the antidiabetic 19.3, 3.5, 3.9, 7.26, 20, 12.08, 2.4, 52.1, 0.08 and 3.91 Saeed et al (1978); Kanjilal et al (1995); Akhila Frontiers in Pharmacology frontiersin.org potency of C. citratus at dosage rates of 400 and 800 mg, by decreasing the levels of insulin (p < 0.001), glucose (p < 0.001) and triglycerides (p < 0.001) (Bharti et al, 2013).…”

Section: Antidiabetic Effectmentioning

confidence: 99%

Review of phytomedicine, phytochemistry, ethnopharmacology, toxicology, and pharmacological activities of Cymbopogon genus

Tibenda

Qian²,

Wang

et al. 2022

Front. Pharmacol.

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The Cymbopogon genus belongs to the Andropoganeae family of the family Poaceae, which is famous for its high essential oil concentration. Cymbopogon possesses a diverse set of characteristics that supports its applications in cosmetic, pharmaceuticals and phytotherapy. The purpose of this review is to summarize and connect the evidence supporting the use of phytotherapy, phytomedicine, phytochemistry, ethnopharmacology, toxicology, pharmacological activities, and quality control of the Cymbopogon species and their extracts. To ensure the successful completion of this review, data and studies relating to this review were strategically searched and obtained from scientific databases like PubMed, Google Scholar, ResearchGate, ScienceDirect, and Elsevier. Approximately 120 acceptable reviews, original research articles, and other observational studies were included and incorporated for further analysis. Studies showed that the genus Cymbopogon mainly contained flavonoids and phenolic compounds, which were the pivotal pharmacological active ingredients. When combined with the complex β-cyclodextrin, phytochemicals such as citronellal have been shown to have their own mechanism of action in inhibiting the descending pain pathway. Another mechanism of action described in this review is that of geraniol and citral phytochemicals, which have rose and lemon-like scents and can be exploited in soaps, detergents, mouthwash, cosmetics, and other products. Many other pharmacological effects, such as anti-protozoal, anti-bacterial, anti-inflammatory and anti-cancer have been discussed sequentially, along with how and which phytochemicals are responsible for the observed effect. Cymbopogon species have proven to be extremely valuable, with many applications. Its phytotherapy is proven to be due to its rich phytochemicals, obtained from different parts of the plant like leaves, roots, aerial parts, rhizomes, and even its essential oils. For herbs of Cymbopogon genus as a characteristic plant therapy, significant research is required to ensure their efficacy and safety for a variety of ailments.

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Section: Antidiabetic Effectmentioning

confidence: 99%

Review of phytomedicine, phytochemistry, ethnopharmacology, toxicology, and pharmacological activities of Cymbopogon genus

Tibenda

Qian²,

Wang

et al. 2022

Front. Pharmacol.

View full text Add to dashboard Cite

show abstract

“…Furthermore, it is readily available at a cost-effective price, is environmentally friendly, and has been endorsed by the community for its distinctive aroma (Zulfikar et al 2019). Besides being used as an essential oil, citronella is also used as a herbal medicine beneficial for the body to maintain glucose, reduce hypertension, anticancer, flatulence, digestive disorders, cramps and intestinal irritation, and gastritis (Widiputri et al 2019).…”

Section: Introductionmentioning

confidence: 99%

Diversity characterization of three varieties of Cymbopogon nardus under different shade conditions

DANATA,

AINI,

UDAYANA

et al. 2023

Biodiversitas

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Abstract. Danata NH, Aini N, Udayana C, Setiawan A, Yamika WSD, Prambudi R. 2023. Diversity characterization of three varieties of Cymbopogon nardus under different shade conditions. Biodiversitas 24: 3574-3582. Cymbopogon nardus L. is a perennial aromatic plant distinguished for producing one of the world's most vital essential oils, citronella. This plant requires abounding sunlight to maximize the growth and quality of essential oils. The development of citronella can be implemented with an agroforestry system as an intercrop. However, the deterring factor restricting the propagation of citronella as an intercrop in agroforestry systems is the unavailability of adequate sunlight, consequently deteriorating the growth and quality of essential oils. This study investigated three varieties of C. nardus, i.e., Seraiwangi 1, Sitrona 1 Agribun, and Sitrona 2 Agribun, at distinctive shade proportions, i.e., 0%, 25%, 50%, and 75% shade. The examined parameters included the growth, physiological responses, yield, and quality of essential oils, i.e., citronellal, citronellol, and geraniol. Results demonstrate that the various types and shade percentages affect most examined parameters. The Seraiwangi 1 variety grown under 0% and 25% shade had nearly the same value, while the Sitrona 1 Agribun and Sitrona 2 Agribun varieties continued to experience declines ranging from 0%, 25%, 50%, to 75%. Nevertheless, shade extensively influences physiological responses such as photosynthetic rate and stomata width, and contrastingly there was a cipher effect on the stomata length. In the yield parameters, the oil concentration declined with the increase in shading percentage. The Seraiwangi 1 delivered superior quality of citronellal, citronellol, and geraniol compared to Sitrona 1 Agribun and Sitrona 2 Agribun varieties.

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“…However, the heating and cooling processes decreased the inhibiting activity of these models (Santoso et al, 2018). In addition, an industrial approach to lemongrass extract as an antidiabetic food ingredient was also studied (Widiputri et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

The IMPACTS OF FORMULATION AND STORAGE ON Α-Glucosidase INHIBITORY ACTIVITY OF LEMONGRASS, GINGER, AND BLACK TEA FUNCTIONAL BEVERAGES

Santoso

Sunardi

Ignatia

et al. 2021

J.Pharm.Sci.Community

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Functional beverages from lemongrass (Cymbopogon citratus), white ginger (Zingiber officinale Roscoe) and black tea (Camelia sinensis) were developed based on their α-glucosidase inhibitory (AGI) activities and sensory acceptance. The AGI was evaluated using in vitro enzymatic assay, while sensory acceptance was tested using affective sensory tests. The evaluation of their aqueous extracts showed that dried lemongrass and ginger possessed higher extraction yield (3.4 %, 2.7 %, respectively), though not necessarily accompanied with a better AGI activity (IC50 24.50 mg/mL, IC50 16.61 mg/mL) than the fresh lemongrass and ginger (2.1 %, 1.8 %, IC50 17.93 mg/ml, IC50 >47.00 mg/mL, respectively). Meanwhile, the evaluation of the combined extract showed additive and synergistic effects. The extract combination formula was selected based on the sensory acceptance, resulting in the beverages containing 4.29 mg/mL of lemongrass, 0.71 mg/mL of ginger, and 1.05 mg/mL of black tea with a total phenolic content of 636.45 mg/L Gallic Acid Equivalent (GAE). The selected formula showed the stability of AGI activity andthe pH value at 4 °C were in accordance with the growth of microbial count that was lower than those stored at 25 °C in a 50-day period. Changes in color and oBrix value were not significantly observed in the samples stored at 25 °C and 4 °C. Lime juice was selected as the additional flavoring agent, which could increase both the palatability and AGI activity of the beverages.

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Benchmarking Study of Cymbopogon citratus and C. nardus for Its Development of Functional Food Ingredient for Anti-diabetic Treatment

Cited by 4 publications

References 0 publications

Review of phytomedicine, phytochemistry, ethnopharmacology, toxicology, and pharmacological activities of Cymbopogon genus

Review of phytomedicine, phytochemistry, ethnopharmacology, toxicology, and pharmacological activities of Cymbopogon genus

Diversity characterization of three varieties of Cymbopogon nardus under different shade conditions

The IMPACTS OF FORMULATION AND STORAGE ON Α-Glucosidase INHIBITORY ACTIVITY OF LEMONGRASS, GINGER, AND BLACK TEA FUNCTIONAL BEVERAGES

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