Bendamustine Monotherapy for Primary Cutaneous Gamma-Delta T-Cell Lymphoma

Abstract

We thank the patients for granting permission to publish this information.1. Toda-Brito H, Aranha JMP, Tavares ES. Lupus miliaris disseminatus faciei.

Bendamustine monochemotherapy in aggressive or advanced‐stage primary cutaneous T‐cell lymphomas

“…7 Moreover, our group has reported a case of primary cutaneous gamma-delta T-cell lymphoma that completely cleared with bendamustine monochemotherapy (see patient 11). 8 In conclusion, this retrospective single-centre analysis revealed an encouraging high ORR of bendamustine monochemotherapy in advanced-stage MF and aggressive CTCL, including elderly patients with comorbidity. In four patients with PR, subsequent maintenance therapy with ECP or bexarotene enabled long-term disease control.…”

Primary Cutaneous Gamma/Delta T-cell Lymphoma Simulating Lupus Erythematosus Panniculitis

“…Therapeutic alternatives include bexarotene, phototherapy, radiotherapy, denileukin diftitox and bendamustine. 5 PCGD-TCL responds poorly to conventional treatments, having an average survival of 31 months. 3 PCGD-TCL needs to be carefully excluded in patients with panniculitis-like lesions unresponsive to therapy.…”

Clinical, Diagnostic and Prognostic Characteristics of Primary Cutaneous Gamma Delta T-cell Lymphomas

“…Bendamustine was used in relapsed/refractory T-cell lymphomas with 28% of patients achieving CR; however, none of these patients in this series had PCGDTL [ 67 ]. In a case report of one patient, bendamustine led to sustained complete remission for more than 12 months [ 68 ].…”