Bending strength and Biological properties of PLA-HA composites for femoral canine bone fixation plate

Sadudeethanakul, Saksorn; Wattanutchariya, Wassanai; Nakkiew, Wasawat; Chaijaruwanich, Anirut; Pitjamit, Siwasit

doi:10.1088/1757-899x/635/1/012004

Cited by 12 publications

(8 citation statements)

References 15 publications

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“…The bending power was investigated by a universal testing machine (UTC). As a conclusion to this research, the optimal bending conditions were found for plates with 5% HAP, 160 o C, 7 Mpa [260].…”

Section: Polymer / Ceramicssupporting

confidence: 52%

Biomaterials With Enhanced Biological Functions for Medical Applications

Balint¹,

Paltinean²,

Tomoaia³

et al. 2021

AnnalsARSciBio

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Biomaterials and their use as implant coatings have been evaluated focusing on biocompatibility, biodegradability and constructive responses in terms of osseointegration, cell proliferation and cell adhesion. Biomaterials from natural (protein and polysaccharide) and synthetic (metallic, polymeric, ceramic and composite) sources have been identified. The role of biomaterials and implant coatings in the body through in vivo and in vitro experiments has been highlighted. In addition, methods for activating the surface of implants such as mechanical, chemical and physical ones are presented, as well as the classification of the deposition procedures but also of the interactions with the living system. This review addresses a topic with future challenges and perspectives in the biomedical field with the well-defined goal of maintaining and enhancing tissue elasticity, facilitating the healing of diseases suffered by patients and developing innovative materials capable of replacing or regenerating affected tissues.

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Section: Polymer / Ceramicssupporting

confidence: 52%

Biomaterials With Enhanced Biological Functions for Medical Applications

Balint¹,

Paltinean²,

Tomoaia³

et al. 2021

AnnalsARSciBio

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“…Additionally, the biocomposite created in this work has a higher flexural modulus than cancellous bone, which has a flexural modulus of 0.05–0.5 GPa [ 24 ]. The matrix’s overall modulus rises as a result of the incorporation of HA powder, since it slows down matrix phase movement around individual particles [ 56 ]. Apart from this, the flexural strength and flexural modulus produced by the biocomposite material increase with the amount of HA that is present.…”

Section: Resultsmentioning

confidence: 99%

Characterization of PLA/PCL/Green Mussel Shells Hydroxyapatite (HA) Biocomposites Prepared by Chemical Blending Methods

et al. 2022

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Recently, there has been an increase in the number of studies conducted on the process of developing hydroxyapatite (HA) to use in biocomposites. HA can be derived from natural sources such as bovine bone. The HA usage obtained from green mussel shells in biocomposites in this study will be explored. The research goal is to investigate the composition effect of biomaterials derived from polycaprolactone (PCL), polylactic acid (PLA), as well as HA obtained from green mussel shells with a chemical blending method on mechanical properties and degradation rate. First, 80 mL of chloroform solution was utilized to immerse 16 g of the PLA/PCL mixture with the ratios of 85:15 and 60:40 for 30 min. A magnetic stirrer was used to mix the solution for an additional 30 min at a temperature and speed of 50 °C and 300 rpm. Next, the hydroxyapatite (HA) was added in percentages of 5%, 10%, and 15%, as well as 20% of the PLA/PCL mixture’s total weight. It was then stirred for 1 h at 100 rpm at 65 °C to produce a homogeneous mixture of HA and polymer. The biocomposite mixture was then added into a glass mold as per ASTM D790. Following this, biocomposite specimens were tested for their density, biodegradability, and three points of bending in determining the effect of HA and polymer composition on the degradation rate and mechanical properties. According to the findings of this study, increasing the HA and PLA composition yields a rise in the mechanical properties of the biocomposites. However, the biocomposite degradation rate is increasing.

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“…In the permanent implantation, a firm chemical and biological bond formation at the junction of material surface and tissue interface. HA, 86,87 Polylactic acid (PLA)-HA, 164 Mg/fluorapatite, 102 silk fibroin/tannic acid/HA, 158 Sr/HA 165 , CNT/HA, 166 Sr/HA, 167,168 Ti/HA, 169 nano TiO 2 /HA, 170 SiO 2 /HA, 171 nano TiO 2 , 172 Si/biphasic calcium phosphate (BCP), 173 dicalcium silicate, 174 wollastonite, 175 and others 176…”

Section: Anti-bacterialmentioning

confidence: 99%

“…Must not elicit an adverse response or reaction to surrounding tissue, compatible to blood, and be integral to the body environment HA, 177 silk fibroin/tannic acid/HA, 158 Sr/HA, 165 Ti/HA, 178 TCP coatings, 179 mxene/HA, 90 collagen/HA, 88 PLA-HA, 164 silk fibroin/tannic acid/HA 158…”

Section: Biocompatibilitymentioning

confidence: 99%

“…The ability of the material to prevent surface mechanical failures under high load-bearing conditions Ti-6Al-4V/HA, 101,180 Ti, 181 graphene/HA, 182,183 Al 2 O 3 /HA, 184 CNT/HA 185,186 Non-carcinogenic Must not elicit carcinogenic material to form an inflammation or cancer Tricalicum Phosphate (TCP), 187 HA, 187 collagen/HA, 88 PLA/ HA, 188 Sr/HA, 189 and others 78,190 Nontoxic Must not release toxic substances that harm the body environment TCP, 187 HA, 187 HA/HA-Mg bi-layer, 191 HA/Al 2 O 3 -SiO 2 bi-layer, 192 GO/CS/HA, 91 PLA-HA, 164 CTAB/HA, 116 Sr/HA, 165…”

Section: Interfacial Stabilitymentioning

confidence: 99%

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