Benign Gynecologic Conditions

Boyle, Kevin J.; Torrealday, Saioa

doi:10.1016/j.suc.2007.12.001

Cited by 20 publications

(18 citation statements)

References 34 publications

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“…There is surprisingly little data on the incidence of uterine fibroids in the general U.S. population for comparison, but the primary paper reporting US data estimated that 70% of Caucasian women and 80% African American women have uterine fibroids by age 50 (Day Baird et al 2003). Uterine fibroids cause symptoms in about 20% of reproductive age women (Boyle and Torrealday 2008). It is difficult to determine the rate of ovarian cysts in the general population since ultrasound cannot distinguish between them and normal or leuteized follicles.…”

Section: Genitourinary Problemsmentioning

confidence: 99%

Cowden Syndrome: A Critical Review of the Clinical Literature

Pilarski

2008

Journal of Genetic Counseling

285

252

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Cowden syndrome (CS) is a multi-system disease involving hamartomatous overgrowth of tissues of all three embryonic origins and increased risks for thyroid, breast and possibly other cancers. Benign breast, thyroid, uterine and skin lesions are also common. Approximately 80% of patients with CS have an identifiable germline mutation in the PTEN gene. The majority of the existing data on the frequencies of component clinical features have been obtained from compilations of case reports in the literature, many of which predate the establishment in 1996 of consensus diagnostic criteria. Many of these reports also suffer from ascertainment bias which emphasized the dermatologic features of the disease. This paper presents an overview of Cowden syndrome focusing on a critical evaluation of the major literature on the component cancers, benign features, and molecular findings in CS, noting the limitations of the published data.

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Section: Genitourinary Problemsmentioning

confidence: 99%

Cowden Syndrome: A Critical Review of the Clinical Literature

Pilarski

2008

Journal of Genetic Counseling

285

252

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“…Leiomyomas present with a limited amount of dot-or eggshell-like calcification with a similar degree of enhancement as Brenner tumors (16). Furthermore, the difference of blood supplies may be detected between Brenner tumor and leiomyomas (17).…”

Section: Discussionmentioning

confidence: 99%

Computed tomography imaging features of benign ovarian Brenner tumors

et al. 2018

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Abstract. The present study aimed to describe the computed tomography (CT) imaging features of ovarian Brenner tumor for diagnostic accuracy and disease understanding. The CT imaging features of 9 cases of ovarian Brenner tumor confirmed by surgery and pathology were retrospectively analyzed and compared. Of the 9 cases of ovarian Brenner tumor, 3 were right located and 6 were left located with clear borders; 7 with round or oval shapes, while 2 were with irregular and lobulated morphology; 5 solid lesions presented with multiple scattered calcification shadows inside with moderate enhancement, while 3 cystic lesions were presented with mixed solid and cystic composition, and significant enhancement was identified in the solid component, but not in the cystic component. Furthermore, papillary projections inside and mild nodular enhancement were observed in one case of cystic lesion. The pathological analysis demonstrated that an epithelium nest composed the tumors with urothelial like cells and fibrous matrix. Of the 9 cases, 5 epithelial nests exhibited adeno-like cystic lumen without cell mitosis phase. All cases were diagnosed with benign ovarian Brenner tumor. Specific CT imaging features of ovarian Brenner tumor can be identified and pathological examinations are required for diagnosis confirmation.

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“…The list of cystic masses of the abdominal cavity is long (Table 1). Size is a major determinant of the clinical diagnosis of such masses; although most adnexal cystic masses are benign, the possibility of malignancy mandates the need for accurate diagnosis and treatment [1,2]. Most authors have suggested that adnexal cysts that are unilocular, unilateral and less than 5 cm are benign [3].…”

Section: Case Report Discussionmentioning

confidence: 99%

Management of a Giant Cystic Mass in a Young Otherwise Healthy Woman

Gaffey¹,

Raper²

2018

ACRI

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A 22-year-old female student presented with pain, early satiety, a dragging sensation in the abdomen, and weight gain. She had been diagnosed with irritable bowel syndrome several years prior based on the symptoms. Over the preceding 6 months, she reported increasing frequency of progressive nausea primarily with meals, emesis nearly every day, and constipation. She noted early satiety but no evidence of dysphagia or odynophagia. Overall, she had a 20-pound weight gain within 4 months prior to diagnosis. The patient had no significant past medical or surgical history. Within her family history, there was no history of ovarian disease, gastrointestinal malignancies, or cystic disease. She reported regular menstrual cycle with an age of menarche of 12. A pregnancy test at admission was negative. Prior to diagnosis she had taken to wearing exclusively yoga pants because belts were uncomfortable.Physical examination was notable for diffuse abdominal distention and a fluid wave without peritonitis or evidence of a hernia. Percussion was dull throughout. A CT scan of the abdomen and pelvis noted a large cystic mass with internal attenuation, occupying the majority of the abdomen with mass effect resulting in superior displacement of the liver, spleen, stomach, as well as the majority of the small bowel located in the left side of the abdomen (Figure 1). Tumor marker studies, including beta-HCG, CA 19-9, carcinoembryonic antigen, and CA125 were negative.After discussion of options including a laparoscopic approach, and the small but real risk of a cancer diagnosis, an open approach was judged best to avoid rupture of the cyst. The patient was taken to the operating room for an exploratory laparotomy. A 40-cm cyst arising from the right ovary was noted (Figure 2) and on full inspection of the abdomen there was a normal appearing uterus, normal left ovary and fallopian tube, normal pelvis and paraaortic lymph nodes, normal peritoneum, and normal bowel. Gynecologists, having obtained prior consent, performed a right oophorectomy and salpingectomy in continuity with the mass. She recovered rapidly with normal dietary intake. The final pathology of the 10.4 kg cyst was serous cystadenofibroma and ovary with hemorrhagic corpus luteum. AbstractWe report a new perspective on the case of a 22-year-old female with no significant medical history who posed a diagnostic and therapeutic challenge; a giant cystic mass of the abdominal cavity. Work up was notable for no significant laboratory abnormalities but a large cystic lesion noted on imaging. The patient underwent open resection. A giant cystic abdominal tumor may present with the common and protean abdominal symptoms of bloating, pain, and early satiety from either mass effect or adhesions to surrounding structures. Caution is advised in attempting the laparoscopic resection of such tumors.

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Benign Gynecologic Conditions

Cited by 20 publications

References 34 publications

Cowden Syndrome: A Critical Review of the Clinical Literature

Cowden Syndrome: A Critical Review of the Clinical Literature

Computed tomography imaging features of benign ovarian Brenner tumors

Management of a Giant Cystic Mass in a Young Otherwise Healthy Woman

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