Benign Orbital Tumors with Bone Destruction in Children

Yan, Jianhua; Zhou, Sheng; Li, Yongping

doi:10.1371/journal.pone.0032111

Cited by 23 publications

(18 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Intraosseous VM and hemangiomas of the orbit and periorbital region are rare findings and, therefore, initially not the first differential diagnosis based on frequency of osseous lesions (38,39). Radiographic differential diagnosis of calvarial lesions of vascular origin includes epidermoid cyst and Langerhans' cell histiocytosis (40).…”

Section: Discussionmentioning

confidence: 99%

Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey

et al. 2020

View full text Add to dashboard Cite

Background/Aim: Intraosseous orbital hemangiomas or vascular malformations (VM) are rare. This report is intended to complement the experience of diagnosing and treating a rare vascular lesion at this site. Special attention is paid to threedimensional imaging and the morphological distinction between the two entities in this location. Case Report: A 54-year-old female was examined and surgically treated for an exophytic firm mass of the infraorbital, which had become palpable as a hard mass due to growth in size. At first, a bone tumor, for example, an osteoma, was suspected. Intraoperatively, an osseous expansion with distinct fenestrations of the newly grown bone's surface, was detected. The lesion was firmly attaching to the orbital rim. The densely vascularized tumor was well defined to the soft tissues but had grown in continuity from the orbital floor and rim. Vascularized cavities caused the tumor to have a slightly reddish color. The histological examination confirmed the suspicion of the lesion's vascular origin. The lesion's immunohistochemical expression profile approved the final diagnosis of intraosseous VM. Conclusion: The symptoms of intraosseous vascular lesions of the orbit are determined by location and size. Modern imaging techniques facilitate the estimation of tumor-like expansion of lesions. However, the imaging characteristics of intraosseous vascular lesions are very variable. The symptoms of the patient presented herein show that growth phases of a vascular orbital malformation can occur in later stages of life and are initially indistinguishable from a neoplasm. In individual cases, patient care necessitates advanced diagnostic measures to establish the diagnosis and determine surgical therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Estas células deben tener tinción positiva con anticuerpos para CD1a, langerina (CD207), además de S-100, los que confirman el diagnóstico. [4][5][6] En nuestro caso, se realizó CD1a y S-100.…”

Section: Discussionunclassified

“…5 Pueden existir casos asintomáticos asociados a la presentación en el hueso o la piel. 6 A pesar de no tener estudios definidos sobre los factores predisponentes, se están encontrando diversas relaciones con la exposición de los padres a solventes, antecedentes familiares de cáncer, como leucemia, cáncer de mama o de pulmón, antecedentes personales o familiares de enfermedad tiroidea, exposición ocupacional de los padres a polvo de metal, granito o madera, etnia hispana y condición socioeconómica precaria. 7,8 El pronóstico se relaciona con la edad; los pacientes menores de 2 años, a pesar de ser considerados de alto riesgo, presentan buena respuesta al tratamiento si no tienen compromiso multisistémico.…”

Section: Introductionunclassified

Histiocitosis de células de Langerhans con afectación de la órbita en un lactante: reporte de un caso

Huidobro-Chávez¹,

Pareja

Pachas-Peña

et al. 2018

Arch Argent Pediatr

View full text Add to dashboard Cite

Presentación de casos clínicos RESUMEN La histiocitosis de células de Langerhans es una enfermedad poco frecuente, caracterizada por la proliferación clonal de células dendríticas mieloides CD1a positivas, asociada a un componente inflamatorio significativo. El compromiso óseo es común; en niños, las lesiones líticas más frecuentes son en la cúpula craneal y son raras las lesiones en la órbita. Se presenta a un lactante de 18 meses que consultó por edema periorbitario y proptosis del ojo derecho de dos meses de evolución. Al momento del examen físico, no se encontraron otras alteraciones. Se realizó una tomografía y una resonancia magnética, que mostraron una masa tumoral en el seno maxilar de crecimiento expansivo y erosión del techo de la órbita. La biopsia confirmó la proliferación CD1a positiva; recibió tratamiento con prednisona y vinblastina, con evolución favorable. Un tratamiento precoz puede evitar secuelas significativas en los pacientes cuando son sensibles al tratamiento. Es una entidad poco frecuente que requiere un alto índice de sospecha y un manejo multidisciplinario. Palabras clave: histiocitosis de células de Langerhans, cavidad nasal, órbita, sistema nervioso central, factores de riesgo.

show abstract

“…Tumor data included orbital location (superior, inferior, anterior, posterior), configuration (round, ovoid, diffuse), size, margin (ill-defined, well-defined), quality (rigid, soft, medium), tenderness (present, absent), tissues or spaces involved, as well as findings from imaging and histopathologic examinations [6].…”

Section: Methodsmentioning

confidence: 99%

Concomitant Intraocular and Orbital Space-Occupied Lesions

Yan¹,

Shen²,

Chen³

2016

Optom open access

Self Cite

View full text Add to dashboard Cite

Purpose/background: Concomitant intraocular and orbital space-occupied lesions are relatively rare and this is the first report stressing the underlying causes of concomitant intraocular and intraorbital lesions. In this paper, we present cases showing both intraocular and orbital soft tissue masses and highlight their clinical, pathological and imaging features. Materials and methods:A retrospective review was performed on cases with both intraocular and orbital spaceoccupied lesions who were treated at the Zhongshan Ophthalmic Center, of Sun Yat-sen University, China between Jan 1, 2000 and Dec 31, 2011. Results:From an initial retrospective review of 1543 patients with a diagnosis of intraocular and/or orbital spaceoccupied lesions, 8 patients (4 males and 4 females) with a coexistence of both intraocular and orbital mass lesions were identified. Patients' ages ranged from 22 months to 71 years (median = 3.0 years) and included 5 cases of retinoblastoma, 1 case of idiopathic inflammatory pseudotumor, 1 case of T-cell lymphoma, and 1 case of SturgeWeber syndrome.Conclusions: Based upon these findings, the presence of a lesion involving both the orbit and eye should be included when a diagnosis of retinoblastoma, idiopathic inflammatory pseudotumor, lymphoma, and/or SturgeWeber syndrome is proposed.

show abstract

Benign Orbital Tumors with Bone Destruction in Children

Cited by 23 publications

References 27 publications

Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey

Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey

Histiocitosis de células de Langerhans con afectación de la órbita en un lactante: reporte de un caso

Concomitant Intraocular and Orbital Space-Occupied Lesions

Contact Info

Product

Resources

About