Berry phenolics selectively inhibit the growth of intestinal pathogens

Puupponen‐Pimiä, Riitta; Nohynek, Liisa; Hartmann-Schmidlin, Susan; Kähkönen, Marketta; Heinonen, Marina; Riihinen, Kaisu R.; Oksman-Caldentey, Kirsi-Marja

doi:10.1111/j.1365-2672.2005.02547.x

Cited by 361 publications

(250 citation statements)

References 25 publications

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“…The bioavailability and effects of polyphenols greatly depend on their transformation by components of the gut microbiota. For example, gram-negative bacteria are more resistant to flavanols owing to their different wall composition, as compared to gram-positive bacteria [26]. Effects can also be modified by bacterial growth and metabolism of flavanols and dark chocolate.…”

Section: Positive Effectsmentioning

confidence: 99%

Use of dark chocolate for diabetic patients: a review of the literature and current evidence

Shah

Alweis

Najim

et al. 2017

Journal of Community Hospital Internal Medicine Perspectives

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Dietary changes are a major lifestyle factor that can influence the progression of chronic diseases such as diabetes. Recently, flavanols, a subgroup of plant-derived phytochemicals called flavonoids, have gained increasing attention, due to studies showing an inverse correlation between dietary intake of flavanols and incidence of diabetes. Flavanoids in the cocoa plant may ameliorate insulin resistance by improving endothelial function, altering glucose metabolism, and reducing oxidative stress. Oxidative stress has been proposed as the main culprit for insulin resistance. The well-established effects of cocoa on endothelial function also points to a possible effect on insulin sensitivity. The relationship between insulin resistance and endothelial function is a reciprocal one. Overall, the evidence from these studies suggests that cocoa may be useful in slowing the progression to type 2 diabetes and ameliorating insulin resistance in metabolic syndrome. Additionally, results from several small studies indicate that cocoa may also have therapeutic potential in preventing cardiovascular complications in diabetic patients. Studies highlighting the potential of cocoa-containing diets, in large-randomized controlled trials should be performed which might give us a better opportunity to analyze the potential health-care benefit for reducing the risk of complications in diabetic patients at molecular level.

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Section: Positive Effectsmentioning

confidence: 99%

Use of dark chocolate for diabetic patients: a review of the literature and current evidence

Shah

Alweis

Najim

et al. 2017

Journal of Community Hospital Internal Medicine Perspectives

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“…The last reports have listed standard cultivars of dark fruited berries (raspberry, blueberry, gooseberries, blackberries) having high natural antioxidant content relative to vegetables or other foods (24,52,65,74,75). In addition to vitamins and minerals, extracts of raspberries are also rich of anthocyanins, other fl avonoids and phenolic acids.…”

Section: Bioactive Compounds In Small Fruits and Their Influence On Hmentioning

confidence: 99%

“…Having more detailed information on the biochemical composition of plant tissues has great potential value in a wide range of both scientifi c and applied fi elds (16,17). Evidences supporting the benefi cial health effects of fruits are indisputable and largely discussed and proved (17,19,25,30,52,72). The number of research projects aiming at determination of bioactive compounds with known plant parentage increases rapidly.…”

Section: Introductionmentioning

confidence: 99%

Bioactive Compounds in small Fruits and their Influence on Human Health

Badjakov

Nikolova

Gevrenova

et al. 2008

Biotechnology & Biotechnological Equipment

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“…Phytochemicals present in black raspberries reduce vascular endothelial growth factor (VEGF) expression, which contributes to metastasis inhibition [23,24]. Many raspberry and blackberry phenolics exhibit antimicrobial [25,26] and antiviral [27] activities. Due to a high content and large diversity of health-beneficial phenolic compounds, raspberry and blackberry fruits can be regarded as natural functional food.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant properties of fruits of raspberry and blackberry grown in central Europe

et al. 2015

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Fruits of several, mainly Polish cultivars of floricane-and primocane-fruiting red raspberry (Rubus idaeus), black raspberry (Rubus occidentalis) and blackberry (Rubus fruticosus), grown in central Europe during two successive vegetation periods, were investigated. The content of phenolic compounds, including anthocyanins, as well as antioxidant properties of fruit extracts were analysed. A number of methods were employed: ferric ion reducing antioxidant power (FRAP), cupric ion reducing antioxidant capacity (CUPRAC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity involving both colorimetric and EPR spectrometric measurements. From among all the tested fruits black raspberries had the largest antioxidant capacity as verified by all methods used in this study. These berries were also the most abundant in phenolic and anthocyanin compounds. Blackberries were characterised by larger antioxidant capacity than red raspberry fruits which were accompanied by higher content of total phenolics and anthocyanins. Berries of primocane-fruiting cultivars, often used for intensive agricultural production, generally did not differ in the total phenolic and anthocyanin content as well as in the antioxidant capacity as compared to the traditional, floricane-fruiting ones. The research contributes to deep characterisation of central European berry fruits which due to their high content and large diversity of health-beneficial compounds are classified as natural functional food.

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Berry phenolics selectively inhibit the growth of intestinal pathogens

Abstract: Antimicrobial properties of berries could be utilized in functional foods. Furthermore these compounds would be of high interest for further evaluation of their properties as natural antimicrobial agents for food and pharmaceutical industry.

Cited by 361 publications

References 25 publications

Use of dark chocolate for diabetic patients: a review of the literature and current evidence

Use of dark chocolate for diabetic patients: a review of the literature and current evidence

Bioactive Compounds in small Fruits and their Influence on Human Health

Antioxidant properties of fruits of raspberry and blackberry grown in central Europe

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