Beryllium Coordination to Bio-Ligands: Isolation from Aqueous Solution and Crystal Structure of a Hexanuclear Complex of Be²⁺ with Glycolic Acid, Na₄[Be₆(OCH₂CO₂)₈]

Stable, Soluble Beryllium Aluminum Citrate Complexes Inspired by the Emerald Mineral Structure

“…Although this mineral structure occurs in nature, there are no organic-based structures containing aluminum and beryllium. A few citrate-type aqueous complexes containing CÀO units bridging two beryllium atoms are known [10,11] and very stable complexes with Be-O-Be linkages with phenolic species acting as bridging oxygen atoms have been recently reported. [12] We report here on the synthesis of a new stable citrate complex containing beryllium and aluminum atoms with a Be-O-Al linkage similar to that of beryl and a related aluminum beryllium citrate structure with bridging phosphate units that is highly soluble (1m) in aqueous phosphate solution (0.5 m).…”

Beryllium binding at neutral pH: The importance of the motif

“…Binding and deprotonation of the aliphatic alcohol group is rare, but has been observed in the case of Al 3+ [21][22][23]. There is one example with Be glycolate in the solid state that has been structurally characterized, although this species has not been characterized in solution [24]. The mixed-metal species containing Al and Be with citric acid has been isolated ((NH 4 ) 6 CA 4 Al 2 Be 2 ) [10].…”

Beryllium (II) Chloride Complexes with Phosphoryl Ligands: A DFT Study

“…Previous studies on beryllium showed that coordination of this small and hard cation with fluoride and oxygen donor compone nts dominates the chemistry, with more interest being focussed on the oxygen functional ligands in terms of the toxicity of the metal [6][7][8][9][10][11]. It was also shown that in systems with multifunctional O/N/S-ligands, such as amino acids or peptides, beryllium appears to be coordinated only to the oxygen centres [12][13][14][15][16][17][18][19][20][21]. More recently, Buchner and Muller reported on beryllium chloride complexes with oxygen-containing bio-relevant functional groups as a model to evaluate the potential beryllium binding sites inside proteins, which is important to understand the mechanism of metal-triggered immune responses [22].…”