A b þ -g discrimination set-up was developed and applied to the 22 Na radioisotope. The radioisotope emits positrons (b þ ) and these positrons create g rays by annihilating with electrons. These annihilation g rays were used here, and the discrimination between these positrons and g rays was investigated by the coincidence measurement between time signals and the energy signals. The detection system presented here uses a 3 inch (diameter) by 3 inch (length) NaI(Tl) inorganic scintillation detector for g detection and 3 inch (diameter) by 3 inch (length) plastic scintillation detector for b þ detection.