Bifidobacterium: The Most Sensitive Member of Gut Microbiota That Interacts with Pulmonary Sarcoidosis

Hidden relationship between sarcoidosis and gut microbiota: recent evidence and future implications

“…Apart from the evidence showing C. acnes' involvement in the granuloma formation in sarcoidosis, there are other microbes more specific to the gut microbiota that interacts with pulmonary sarcoidosis. Nasiri et al [16] noted significant changes in the composition and quantities of gut microbiota particularly Bifidobacterium in murine models of sarcoidosis indicating a significant relationship between gut microbiota and sarcoidosis. Despite these pieces of evidence [17], the consensus as per the current evidence does not support a causal relationship between these pathogens and sarcoidosis, and future studies are required to accurately demarcate any role of pathogens in the disease process.…”