Big Data Challenges from an Integrative Exposome/Expotype Perspective

Martín-Sánchez, Fernando

doi:10.1007/978-3-030-06109-8_11

Cited by 4 publications

(2 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, due to the rapid development of technology, the implementation and integration of such tools and platforms is heterogeneous, leading to calls for their greater understanding, and creation of a better-defined process for such utilizations [25][26][27] . This need is more pronounced in the case of a relatively recent concept such as the exposome [28][29][30][31] . Importantly, the sub-theme of understanding the limitations of exposome research has also emerged, in line with previously published work 32,33 .…”

Section: Discussionmentioning

confidence: 99%

Creating personas for exposome research: the experience from the HEAP project

Coombs¹,

Wootton²,

Dillner³

et al. 2023

Open Res Europe

View full text Add to dashboard Cite

The exposome is a complex scientific field that has enjoyed consistent growth over the last two decades, defined as the composite of every exposure to which an individual is subjected from conception to death. The study of the exposome requires consideration of both the nature of those exposures and their changes over time, and as such necessitates high quality data and software solutions. As the exposome is both a broad and a recent concept, it is challenging to define or to introduce in a structured way. Thus, an approach to assist with clear definitions and a structured framework is needed for the wider scientific and public communication. Results: A set of 14 personas were developed through three focus groups and a series of 14 semi-structured interviews. The focus groups defined the broad themes specific to exposome research, while the sub-themes emerged to saturation via the interviews process. Personas are imaginary individuals that represent segments/groups of real people within a population. Within the context of the HEAP project, the created personas represented both exposome data generators and users. Conclusion: Personas have been implemented successfully in computer science, improving the understanding of human-computer interaction. The creation of personas specific to exposome research adds a useful tool supporting education and outreach activities for a complex scientific field.

show abstract

Section: Discussionmentioning

confidence: 99%

Creating personas for exposome research: the experience from the HEAP project

Coombs¹,

Wootton²,

Dillner³

et al. 2023

Open Res Europe

View full text Add to dashboard Cite

show abstract

“…A comparative review of four climate health monitoring devices for individuals to monitor their personal air pollution exposure continuously ( 32 ) reminds us that climate health informatics must integrate and interpret large volumes of data from diverse, non-standard, non-traditional sources. The management at scale of all sorts of climate health data, and the ability to analyze their complex interactions with other human health data for personalized care, will rely on exposome informatics, a field still in development ( 33 ). Further advances managing in human health in the era of climate change will require information systems that capture, process, and communicate combined data on human, animal and plant health, in order to work with complex challenges such as syndemics ( 34 ).…”

Section: Health Informatics Is Needed To Integrate Climate-related Hu...mentioning

confidence: 99%

Climate Change, Human Health, and Health Informatics: A New View of Connected and Sustainable Digital Health

Gray

2022

Front. Digit. Health

View full text Add to dashboard Cite

The connection between human health and climate change has had a scientific basis for many decades. However, little attention has been directed to applying the science of health informatics to this aspect of health and healthcare until recently. This paper briefly reviews examples of recent international work on two fronts: to consider how health informatics can reduce the carbon footprint of healthcare, and to consider how it can integrate new kinds of data for insights into the human health impacts of climate change. Health informatics has two principles of fundamental relevance to this work - connectedness, in other words linking and integrating health data from multiple sources; and sustainability, in other words making healthcare overall more efficient and effective. Deepening its commitment to these principles will position health informatics as a discipline and a profession to support and guide technological advances that respond to the world's climate health challenges.

show abstract

The ethical aspects of exposome research: a systematic review

et al. 2023

View full text Add to dashboard Cite

In recent years, exposome research has been put forward as the next frontier for the study of human health and disease. Exposome research entails the analysis of the totality of environmental exposures and their corresponding biological responses within the human body. Increasingly, this is operationalized by big-data approaches to map the effects of internal as well as external exposures using smart sensors and multi-omics technologies. However, the ethical implications of exposome research are still only rarely discussed in the literature. Therefore, we conducted a systematic review of the academic literature regarding both the exposome and underlying research fields and approaches, to map the ethical aspects that are relevant to exposome research. We identify five ethical themes that are prominent in ethics discussions: the goals of exposome research, its standards, its tools, how it relates to study participants and the consequences of its products. Furthermore, we provide a number of general principles for how future ethics research can best make use of our comprehensive overview of the ethical aspects of exposome research. Lastly, we highlight three aspects of exposome research that are most in need of ethical reflection: the actionability of its findings, the epidemiological or clinical norms applicable to exposome research and the meaning and action-implications of bias.

show abstract

Big Data Challenges from an Integrative Exposome/Expotype Perspective

Cited by 4 publications

References 41 publications

Creating personas for exposome research: the experience from the HEAP project

Creating personas for exposome research: the experience from the HEAP project

Climate Change, Human Health, and Health Informatics: A New View of Connected and Sustainable Digital Health

The ethical aspects of exposome research: a systematic review

Contact Info

Product

Resources

About