Bilateral Full Thickness Macular Holes in Association With Serpiginous Choroiditis

Gregory, Maria Elena; Bhatt, Uday; Benskin, Sherwin; Banerjee, Somnath

doi:10.3109/09273940903105128

Cited by 13 publications

(6 citation statements)

References 5 publications

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“…Review of FA pictures as well as serial OCT examinations are crucial to rule out the presence of CNV, macular holes, and cystoid macular edema. 59,166 …”

Section: Complicationsmentioning

confidence: 99%

Serpiginous Choroiditis and Infectious Multifocal Serpiginoid Choroiditis

Khanamiri

Rao

2013

Survey of Ophthalmology

176

120

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Serpiginous choroiditis (SC) is a posterior uveitis displaying a geographic pattern of choroiditis, extending from the juxtapapillary choroid and intermittently spreading centrifugally. The choroiditis involves the overlying retinal pigment epithelium, and the outer retina. This intraocular inflammation typically involves both eyes in otherwise healthy, middle-aged individuals with no familial or ethnic predilection. Pathogenesis is unclear; however, based on limited histopathologic studies, favorable response to immunosuppressive agents, and the absence of association with systemic or local infectious or noninfectious diseases, an organ-specific autoimmune inflammation seems likely to be the underlying process. Patients, particularly from tuberculosis-endemic regions, may present with fundus changes simulating SC, but show evidence of active tuberculosis and/or the presence of mycobacterial DNA in the aqueous humor. This has been referred to as serpiginous-like choroiditis, but we prefer the description multifocal serpiginoid choroiditis (MSC). We present the distinguishing features of SC and infectious multifocal serpiginoid choroiditis simulating SC. The distinction is crucial to avoid unnecessarily treating SC with antimicrobial agents. Advances in diagnostic and imaging modalities can help differentiate SC from MSC. Novel local and systemic treatment approaches improve the outcome and preserve vision in SC.

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“…Review of FA pictures as well as serial OCT examinations are crucial to rule out the presence of CNV, macular holes, and cystoid macular edema. 59,166 …”

Section: Complicationsmentioning

confidence: 99%

Serpiginous Choroiditis and Infectious Multifocal Serpiginoid Choroiditis

Khanamiri

Rao

2013

Survey of Ophthalmology

176

120

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“…The literature reports 55 cases of macular hole secondary to posterior uveitis (Table 1): 35 Behcet's disease [5-11], 3 idiopathic intermediate uveitis [9], 2 idiopathic posterior uveitis [9], 1 bilateral intermediate uveitis [12], 2 Bartonella henselae [13,14], 2 toxoplasmosis [15,16], 2 Vogt-Koyanagi-Harada [17], 1 cytomegalovirus (CMV) retinitis [9], 1 HLA B27 uveitis [18], 1 bilateral anterior uveitis [19], 1 serpiginous choroiditis [20], 1 fungal endophthalmitis [21], 1 T/natural killer (NK) lymphoma [22], 1 presumed histoplasmosis [23], and 1 immune recovery uveitis in an AIDS patient after CMV retinitis [24]. …”

Section: Discussionmentioning

confidence: 99%

Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review

Bonnin

Cornut

Chaise

et al. 2013

J OPHTH INFLAMM INFECT

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The occurrence of a macular hole due to posterior uveitis is infrequently reported. We report the evolution of three cases of macular holes secondary to posterior segment inflammation. A complete inflammatory and infectious assessment found one case of toxocariasis, one of sarcoidosis, and one of syphilis. After medical etiological treatment, macular hole closure was rapidly obtained in all the cases and confirmed by spectral domain optic coherence tomography, with visual acuity improvement. Fibrous scarring developed in two cases, and foveal photoreceptor complex normalization was observed in the sarcoidosis case. These observations demonstrate that macular holes secondary to posterior uveitis frequently resolve without surgical intervention and so could be underdiagnosed if the patient is not evaluated at the time of onset before spontaneous hole closure.

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“…Macular hole is one of the complications of posterior uveitis [1,2]. The newer diagnostic tools, fundus Autofluorescence, OCT and indocyanine green angiography plays a important role in the management of posterior uveitis.…”

Section: Discussionmentioning

confidence: 99%

“…There are only few reports of macular hole with ocular inflammatory disorders. Maria et al have reported bilateral macular hole associated with serpigenous chroidits [1]. Sheu et al have reported full thickness macular hole associated with behcets disease [2].…”

Section: Introductionmentioning

confidence: 99%

The Anatomical and Clinical Outcome of Conventional Macular Hole Surgery Associated with Serpigenous Choroiditis

Pai¹,

Lootah²,

Taryam³

2011

J Clinic Experiment Ophthalmol

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Bilateral Full Thickness Macular Holes in Association With Serpiginous Choroiditis

Abstract: Macular hole may be another posterior segment complication of serpiginous choroiditis.

Cited by 13 publications

References 5 publications

Serpiginous Choroiditis and Infectious Multifocal Serpiginoid Choroiditis

Serpiginous Choroiditis and Infectious Multifocal Serpiginoid Choroiditis

Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review

The Anatomical and Clinical Outcome of Conventional Macular Hole Surgery Associated with Serpigenous Choroiditis

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