Bilateral primary breast lymphoma masquerading as lactating mastitis

Antoniou, Stavros A.; Antoniou, George Α.; Makridis, C.; Spyrou, Anastassia; Malkotsi, Triada

doi:10.1016/j.ejogrb.2010.05.015

Cited by 5 publications

(3 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These are most often cases of pure primary squamous cell carcinoma of the breast [15–18] but also primary lymphoma [18, 19] or even lymphoepithelioma-like carcinoma originally presented as an abscess, although it is very rare [20]. Even in breastfeeding an abscess may turn out to be cancer [21].…”

Section: Discussionmentioning

confidence: 99%

Breast Abscessed Cancer in Nonlactating Women in Tropical Environment: Radiological, Bacteriological, and Anatomopathological Features about 3 Cases

Tchaou

Darré

Amavi

et al. 2017

Case Reports in Radiology

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Breast Abscessed Cancer in Nonlactating Women in Tropical Environment: Radiological, Bacteriological, and Anatomopathological Features about 3 Cases

Tchaou

Darré

Amavi

et al. 2017

Case Reports in Radiology

View full text Add to dashboard Cite

show abstract

“…Primary squamous cell carcinoma of the breast is rare, accounting for less than 0.4% of all cases of breast cancer. (5) There are also reports of primary breast B-cell lymphoma that present with the initial clinical image of breast sepsis -Sun et al (9) and Antoniou et al (10) reported a unilateral and a bilateral case, respectively. The patients in those two reports did not harbour a typical abscess despite the highly inflammatory clinical features of the breast.…”

Section: Discussionmentioning

confidence: 99%

Lactating breast abscess: a rare presentation of adenosquamous breast carcinoma

Alipour

Seifollahi

Anbiaee

2013

smedj

View full text Add to dashboard Cite

C a s e R e p o r t e247 I NTRO D U C TIO NInflammatory disorders of the breast, including mastitis and breast abscesses, are generally benign diseases that rarely harbour malignancy. Although the occurrence of cancer is not anticipated in true breast abscesses in nursing mothers, it can occasionally happen. Herein, we present a rare case of adenosquamous carcinoma of the breast in a 33-year-old lactating woman who presented with a breast abscess. CA S E R EPO RTA 33-year-old lactating woman presented to our breast clinic with signs of inflammation in her left breast -the skin was largely erythematous and warm over a tender 10-cm fluctuating mass, and several soft, non-suspicious lymphadenopathies were observed in the left axilla. According to the patient, the inflammation began two months prior to presentation and temporarily subsided with the use of oral antibiotics; when the use of oral antibiotics was discontinued, the inflammation flared up. Ultrasonography performed one month prior to presentation showed a multiloculated 93-mm × 82-mm × 63-mm fluidcontaining cavity in the left breast, which was suggestive of a breast abscess, and large reactive axillary lymph nodes in the same side.Intravenous antibiotics were prescribed, lactation ceased, and the cavity was surgically drained, yielding more than 300 mL of diluted pus. As routinely done in our institution, multiple biopsies were performed using the tissue obtained from the abscess wall. of the chest, abdomen and pelvis, and a bone scan of the whole body, was negative. The patient had no family history of breast cancer, and no other known risk factor was detected.Before proceeding with cancer treatment, we had to first determine whether the abscess was an inflammatory carcinoma or an invasive noninflammatory carcinoma presenting as an abscess. Although the inflammatory signs of the breast were in favour of the former diagnosis, a mismanaged large and persistent breast abscess is not uncommon in milk-laden breasts. Hence, the possibility of a lactating abscess superimposed on a typical invasive tumour was considered. However, since the pathologist who reviewed the histology slides could not detect any cancerous involvement in the dermal lymphatics, it was decided that the disease would be treated as a large noninflammatory invasive breast cancer.Following the diagnosis, the surgical wound was immediately closed to allow rapid initiation of neoadjuvant chemotherapy, which involved four cycles of treatment with cyclophosphamide, epirubicin and 5-fluorouracil, followed by four cycles of treatment with taxotere. As the patient did not consent to a mastectomy, breast-conserving surgery with a wide normal margin and axillary dissection was performed. The postoperative course was uneventful. Postoperative radiotherapy consisted of a 5,000-cGy breast and regional lymphatic area irradiation and a 1,000-cGy irradiation boost to the tumour bed. ABSTRACT We report the case of a 33-year-old lactating woman who presented with a 10-cm breast abscess.Biopsy of the abscess w...

show abstract

“…The occurrence of malignant lymphoma after delivery is an extremely rare event. Although several cases of Hodgkin lymphoma and B cell lymphoma of the breast, and one case of PTCL at 3 months after delivery have been reported [ 1 – 6 ], there are no reports of autopsy case of PTCL in the puerperal period. We herein report the first autopsy case of PTCL that occurred exclusively in the puerperal period.…”

Section: Introductionmentioning

confidence: 99%

An autopsy case of peripheral T cell lymphoma occurring in a postpartum woman: a unique case suggesting changes in the immunocharacteristics of lymphoma cells before and after delivery

et al. 2018

View full text Add to dashboard Cite

BackgroundThe occurrence of malignant lymphoma after delivery is an extremely rare event. Although several cases of Hodgkin lymphoma and B cell lymphoma and a few cases of peripheral T cell lymphoma (PTCL) after delivery have been reported, there are no report of autopsy cases of PTCL in the puerperal period.Case presentationA 32-year-old Japanese woman with a past medical history of atopic dermatitis and bronchial asthma presented with generalized eruptions four days after the delivery of her first child; generalized skin induration and lymphadenopathy subsequently emerged. A skin biopsy specimen showed the diffuse proliferation of atypical lymphoid cells that were immunohistochemically-positive for CD4 but negative for CD8. She was diagnosed as PTCL, not otherwise specified (PTCL, NOS). She died one year and three months after the onset of symptoms. At autopsy, the systemic infiltration of lymphoma cells into the whole body was observed. Unexpectedly, these lymphoma cells were immuno-reactive with CD8 but not with CD4.ConclusionThe occurrence and development of PTCL after delivery with the shift from CD4 positivity to CD8 positivity may be associated with not only the selection of resistant subclone as a result of chemotherapy but also the changes of immune status before and after delivery.

show abstract

Bilateral primary breast lymphoma masquerading as lactating mastitis

Cited by 5 publications

References 3 publications

Breast Abscessed Cancer in Nonlactating Women in Tropical Environment: Radiological, Bacteriological, and Anatomopathological Features about 3 Cases

Breast Abscessed Cancer in Nonlactating Women in Tropical Environment: Radiological, Bacteriological, and Anatomopathological Features about 3 Cases

Lactating breast abscess: a rare presentation of adenosquamous breast carcinoma

An autopsy case of peripheral T cell lymphoma occurring in a postpartum woman: a unique case suggesting changes in the immunocharacteristics of lymphoma cells before and after delivery

Contact Info

Product

Resources

About