Bilateral primary renal lymphoma in a pediatric patient: Staging and response evaluation with 18F-FDG PET/CT

Dhull, Varun Singh; Mukherjee, Anirban; Karunanithi, Sellam; Durgapal, Prashant; Bal, Chandrasekhar; Kumar, Rakesh

doi:10.1016/j.remn.2014.05.004

Cited by 15 publications

(18 citation statements)

References 8 publications

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“…Even though the most common manifestation is bilateral renal involvement, acute renal failure, anemia, hematuria, fatigue, and musculoskeletal pains there are few case reports of unilateral involvement. [ 2 3 ] Both T- and B-cell renal lymphoma has been reported. [ 2 9 ] In this present case, it manifested as single kidney involvement with no systemic symptoms or renal failure.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 3 ] Both T- and B-cell renal lymphoma has been reported. [ 2 9 ] In this present case, it manifested as single kidney involvement with no systemic symptoms or renal failure. The patient was 10-year-old, on initial radiological findings, there was suspicion of Wilms tumor, and he underwent nephrectomy.…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] PRL is a rare diagnosis in pediatric age group. [ 2 3 ] Secondary involvement of kidneys in lymphoma is very common entity but primary involvement is rare. [ 4 ] PRL in pediatric age groups manifest as bilateral renal involvement, renal failure, and anemia.…”

Section: Introductionmentioning

confidence: 99%

“…[ 4 ] PRL in pediatric age groups manifest as bilateral renal involvement, renal failure, and anemia. [ 2 3 ] There is no standard treatment approach in case of PRL in children. [ 2 5 ] We report a very interesting case in a 10-year-old boy presenting as unilateral renal involvement, without any symptoms.…”

Section: Introductionmentioning

confidence: 99%

“…[ 2 3 ] There is no standard treatment approach in case of PRL in children. [ 2 5 ] We report a very interesting case in a 10-year-old boy presenting as unilateral renal involvement, without any symptoms. With a suspicion of Wilms tumor, he underwent nephrectomy.…”

Section: Introductionmentioning

confidence: 99%

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Renal Lymphoma: Primary or first manifestation of aggressive pediatric B-cell lymphoma

Coca

Linga

Gundeti

et al. 2017

Indian J Med Paediatr Oncol

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Renal lymphoma is an uncommon renal tumor in children. Unlike renal lymphomas presenting as bilateral disease and renal failure, we report a boy who presented with unilateral renal involvement. After initial nephrectomy, he achieved remission with multiagent chemotherapy but relapsed systemically within 3 months. He was initiated on salvage chemotherapy with autologous bone marrow transplant. Even though the initial manifestation was localized lymphoma eventually, it turned out to be a systemic disease. He succumbed to disease at 14 months from diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Renal Lymphoma: Primary or first manifestation of aggressive pediatric B-cell lymphoma

Coca

Linga

Gundeti

et al. 2017

Indian J Med Paediatr Oncol

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Primary renal sarcoma with SS18::POU5F1 gene fusion

Argani

Matoso

Gross

et al. 2022

Genes Chromosomes & Cancer

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We report the first case of a primary renal undifferentiated sarcoma harboring an SS18::POU5F1 gene fusion. The patient was a 38 year‐old male diagnosed with a 5 cm renal tumor which invaded the adrenal gland and extended into the renal vein. Microscopically, the neoplasm had a predominantly undifferentiated round cell morphology, with areas of rhabdoid and spindle cell growth. Similar to the previously reported cases with this fusion, by immunohistochemistry the neoplasm expressed S100 protein and epithelial markers (diffuse EMA, focal cytokeratin), suggesting the possibility of a myoepithelial phenotype. This report documents another example of a fusion‐positive undifferentiated soft tissue sarcoma occurring as a primary renal neoplasm, adding to the already broad list of such entities. It highlights the crucial role of molecular analysis in establishing a specific diagnosis given the overlapping morphology and immunophenotypes such entities may exhibit.

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