Biliary and plasma copper and zinc in pregnant  Simmental and Angus cattle

Gooneratne, Ravi; Laarveld, B.; Pathirana, K. K.; Christensen, David A.

doi:10.4102/ojvr.v80i1.577

Cited by 4 publications

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the D-and L-enantiomers exist, only D-PENA is clinically useful, while the L-PENA has an excessive toxicity. D-PENA has been used for the treatment of Wilson's disease [25], heavy metal poisoning [26], polyarthritis cystinuria [27], and rheumatoid arthritis [28].…”

Section: The Role Of Thiols In Biological Systemsmentioning

confidence: 99%

Capillary electrophoresis in the analysis of biologically important thiols

2016

View full text Add to dashboard Cite

In this review article, CE methods for analysis of biologically important thiols are overviewed. The article covers the period from the previously published comprehensive review in 2004 until mid-2016, with emphasis on various detection modes, novel approaches for sample preconcentration, and applications in clinical practice. The most commonly used detection methods, such as conductometry or absorbance detection, although universally applicable and available in most commercial instruments have low sensitivity and have only limited use in thiol analysis. Amperometric and MS detection are more sensitive and have their steady place in thiol analysis, although the mainstay remains CE with LIF detection, reaching nanomolar concentration sensitivities for most of the thiols. Novel probes for CE-LIF have been developed and tested. The preconcentration approaches using modified gold nanoparticles reaching excellent sensitivities in the picomolar range and various sample stacking methods are also reviewed. Finally, significant clinical applications of the developed methods are discussed with critical insights into the future of CE analysis of thiols.

show abstract

Section: The Role Of Thiols In Biological Systemsmentioning

confidence: 99%

Capillary electrophoresis in the analysis of biologically important thiols

2016

View full text Add to dashboard Cite

show abstract

Trace Element Concentrations in Beef Cattle Related to the Breed Aptitude

Pereira

Carbajales

López‐Alonso

et al. 2018

Biol Trace Elem Res

View full text Add to dashboard Cite

Animal feed has traditionally been supplemented with trace elements at dietary concentrations well above physiological needs. However, environmental concerns have led to calls for better adjustment of mineral supplementation to actual physiological needs and, in this context, consideration of breed-related differences in trace element requirements. The aim of this study was to analyze trace element concentrations in the main breeds used for intensive beef production in northern Spain (Holstein-Friesian [HF], Galician Blonde [GB], and GB × HF cross). Samples of blood, internal organs, and muscle were obtained at slaughter from 10 HF, GB, and GB × HF cross calves in the same feedlot. Overall, trace element concentrations in serum and internal organs were within adequate ranges and did not differ between those of breeds, suggesting that trace mineral supplementation was adequate in all groups. The only exception to this was copper, and hepatic copper concentrations were above adequate levels in all calves. This was particularly evident in the HF calves, and the maximum recommended level for human consumption was exceeded in 90% of these animals. Copper, iron, manganese, selenium, and zinc concentrations in muscle were significantly higher in the HF than those in the GB calves, with intermediate values for the crosses. These breed-related differences in trace element concentrations in the muscle may be related to lower muscle mass and/or higher hepatic activity in the HF (dairy) calves than in GB (beef) calves. As meat is an essential source of highly available trace elements in human diets, breed-related differences in trace element concentrations in meat deserve further investigation.

show abstract

Zearalenone (ZEN) metabolism and residue concentrations in physiological specimens of dairy cows exposed long-term to ZEN-contaminated diets differing in concentrate feed proportions

Dänicke

Keese

Meyer

et al. 2014

Archives of Animal Nutrition

View full text Add to dashboard Cite

A long-term feeding experiment with dairy cows was performed to investigate the effects of feeding a Fusarium toxin contaminated (FUS) and a background-contaminated control (CON) ration with a mean concentrate feed proportion of 50% during the first 11 weeks after parturition (Groups FUS-50, CON-50, Period 1), and with concentrate feed proportions of 30% or 60% during the remaining 17 weeks (Groups CON-30, CON-60, FUS-30 and FUS-60, Period 2), on zearalenone (ZEN) residue levels in blood serum, milk, urine and bile. ZEN, α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL), zearalanone (ZAL), α-zearalanol (α-ZAL) and β-zearalanol (β-ZAL) were determined by HPLC with fluorescence detection. The ZEN concentrations of the rations fed to Groups CON-50, FUS-50 (Period 1), CON-30, CON-60, FUS-30 and FUS-60 (Period 2) amounted to 53.1, 112.7, 35.0, 24.4, 73.8 and 72.5 µg/kg dry matter, respectively. The concentrations of ZEN, α-ZEL, β-ZEL, ZAN, α-ZAL and β-ZAL in serum, urine and milk were lower than 1, 1, 4, 100, 50 and 200 ng/g, respectively, while ZEN, α-ZEL and β-ZEL were detected in bile. Their levels changed with oral ZEN exposure in the course of the experiment and in a similar direction with concentrate feed proportion (Period 2 only). Thus the proportions of the individual β-ZEL, α-ZEL and ZEN concentrations of their sum varied only in narrow ranges of 68-76%, 6-13% and 12-20%, respectively. Interestingly, the bile concentrations of β-ZEL, α-ZEL and ZEN of Groups CON-60 and FUS-60 amounted to only approximately 50%, 45% and 62%, respectively, of those of Groups CON-30 and FUS-30 despite a similar or even lower ZEN exposure. The results indicate that conversion of ZEN to its detectable metabolites was not changed by different dietary concentrate feed proportions while their absolute levels were decreased. These findings might suggest concentrate feed proportion-dependent and rumen fermentation-mediated alterations in ZEN/metabolite degradation, and/or liver associated alterations in bile formation and turnover.

show abstract

Biliary and plasma copper and zinc in pregnant Simmental and Angus cattle

Cited by 4 publications

References 34 publications

Capillary electrophoresis in the analysis of biologically important thiols

Capillary electrophoresis in the analysis of biologically important thiols

Trace Element Concentrations in Beef Cattle Related to the Breed Aptitude

Zearalenone (ZEN) metabolism and residue concentrations in physiological specimens of dairy cows exposed long-term to ZEN-contaminated diets differing in concentrate feed proportions

Contact Info

Product

Resources

About