Biliary atresia: the development, pathological features, and classification of the bile duct

Liu, Shaowen; Li, Tengfei; Yang, Qianhui; Ke, Xingyuan; Zhan, Jianghua

doi:10.1007/s00383-023-05627-3

Pediatr Surg Int

2024

DOI: 10.1007/s00383-023-05627-3

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Biliary atresia: the development, pathological features, and classification of the bile duct

Shaowen Liu,

Tengfei Li,

Qianhui Yang

et al.

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2024

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Cited by 3 publications

References 61 publications

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A Feasibility Study on 3-D Imaging of Intrahepatic Bile Ducts in Patients with Biliary Atresia Using Airy Beam Excited Two-Photon Microscopy

Musha,

Zhao,

Zhao

et al. 2024

Appl Biochem Biotechnol

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A Feasibility Study on 3-D Imaging of Intrahepatic Bile Ducts in Patients with Biliary Atresia Using Airy Beam Excited Two-Photon Microscopy

Musha,

Zhao,

Zhao

et al. 2024

Appl Biochem Biotechnol

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Features of Morphological and Morphometric Parameters of Lymphoid Structures in Biliary Atresia

Aliyeva

2024

WOMAB

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Laparoscopic vs. open portoenterostomy for biliary atresia: a meta-analysis of pediatric surgical outcomes

Zhu,

Wu,

Cai

et al. 2024

Front. Pediatr.

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BackgroundThe pivotal importance of surgical treatment for pediatric biliary atresia is well-established. This systematic review and meta-analysis was designed to assess the comparative efficacy and safety of open portoenterostomy (OPE) and laparoscopic portoenterostomy (LPE) in managing this condition, providing valuable guidance for clinical decision-making.MethodsA comprehensive literature review was conducted by two researchers in databases such as PubMed, up to July 10, 2024, focusing on studies that evaluated the role of LPE vs. OPE. Data analysis was performed utilizing the RevMan 5.4 software suite.ResultsThe meta-analysis incorporated findings from 15 studies involving a total of 964 pediatric patients with biliary atresia. LPE was associated with decreased intraoperative blood loss [Mean Difference (MD) = −10.80, 95% Confidence Interval (CI) (−13.54, −8.05)] and shortened hospital stay [MD = −2.18, 95% CI (−3.69, −0.67)]. Conversely, the operative time for LPE was considerably longer when compared to OPE [MD = 35.45, 95% CI (26.17, 44.72)]. No significant disparities were noted in the postoperative jaundice clearance rate [Odds Ratio (OR) = 0.98, 95% CI (0.71, 1.35)], incidence of postoperative cholangitis [OR = 0.96, 95% CI (0.66, 1.39)], the rate of liver transplantation between the two surgical approaches [OR = 0.69, 95% CI (0.32, 1.48)], or 2-year survival of the native liver [OR = 1.10, 95% CI (0.67, 1.80)].ConclusionLPE offers more advantages over OPE, including diminished invasiveness and expedited recovery. These benefits suggest that LPE is an emerging and viable alternative in the clinical management of biliary atresia, warranting further investigation and consideration in surgical practice.

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Biliary atresia: the development, pathological features, and classification of the bile duct

Cited by 3 publications

References 61 publications

A Feasibility Study on 3-D Imaging of Intrahepatic Bile Ducts in Patients with Biliary Atresia Using Airy Beam Excited Two-Photon Microscopy

A Feasibility Study on 3-D Imaging of Intrahepatic Bile Ducts in Patients with Biliary Atresia Using Airy Beam Excited Two-Photon Microscopy

Features of Morphological and Morphometric Parameters of Lymphoid Structures in Biliary Atresia

Laparoscopic vs. open portoenterostomy for biliary atresia: a meta-analysis of pediatric surgical outcomes

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