“…Cyclopeptides play various roles in living organisms, where there are e.g. hormones, toxins, antibiotics and molecules with the enzymatic or transporting functions [7][8][9]. One from the most known cyclopeptides is the valinomycin, which is able to bind alkali metal ions and transport them through biological membranes [10].…”
“…Cyclopeptides play various roles in living organisms, where there are e.g. hormones, toxins, antibiotics and molecules with the enzymatic or transporting functions [7][8][9]. One from the most known cyclopeptides is the valinomycin, which is able to bind alkali metal ions and transport them through biological membranes [10].…”
“…Cyclopeptides play a variety of roles in living organisms; indeed they may act as hormones, toxins, antibiotics, molecules with enzymatic functions or as carrier molecules [1][2][3][4]. The most known is valinomicin, cyclopeptide is able of binding the alkali metal ions and transporting them through the biological membranes [1].…”
“…1 has shown binding with human serum albumin and the analog of 1 has also shown affinity with hepatocellular peptide binding proteins from plasma membrane and cytosol of rats. 10 1 has shown immunosuppressive activity comparable to cyclosporine A (CsA) and, therefore, it might be used in a clinical setting. 3 Of all the LOs, 1 suppressed human peripheral blood lymphocyte proliferation aer concanavalin A treatment with an IC 50 of 2.5 mg mL À1 .…”
Bioactive orbitides (linusorbs) from flaxseed (Linum usitatissimum L.) were ligated through methionine with resin to form an affinity column that selectively binds chicken apolipoprotein A1 from chicken serum.
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