Bio-inspired supramolecular self-assembly towards soft nanomaterials

Lin, Yiyang; Mao, Chuanbin

doi:10.1007/s11706-011-0141-5

Cited by 44 publications

(21 citation statements)

References 179 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some organic components, however, are difficult to crystallise, especially larger molecules such as peptides and polypeptides. However, many bio-inspired organic compounds and peptides have been observed to self-assemble [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]41,44,[50][51][52][53][54][55][56][57][58][59][60][61], but the possibility of rapid self-assembly as purification method for peptides and analogous compounds has gone, until now, unrecognised. Figure 7.…”

Section: Discussionmentioning

confidence: 99%

Bidirectional solid phase synthesis of a model oligoglycine bolaamphiphile and purification by rapid self‐assembly

Naidoo

Rautenbach

2012

Journal of Peptide Science

View full text Add to dashboard Cite

We utilised a simple bidirectional (N→C and C→N) solid phase synthesis strategy entailing conventional solid phase peptide synthesis and fragment condensation with a water-soluble carbodiimide to synthesise a model anionic glycylglycine bolaamphiphile containing a suberic acid linker moiety, namely N,N'-suberoyldiglycylglycine. The synthetic suberoyldiglycylglycine was purified using its inherent ability to rapidly self-assemble in an aqueous acidic solution (0.1% trifluoroacetic acid). Monitoring of the rapid assembly process corroborated our visual observation and confirmed packing-directed self-assembly rather than non-specific aggregation or precipitation. The progress of suberoyldiglycylglycine self-assembly was observed to be via the formation of oligomers in the solution, which then self-assembled to form layered β-sheet type macrostructures. Within 24 h, nanotubes grew from these macrostructures and eventually combined to formed microtubes, which we isolated after 5-7 days.

show abstract

Section: Discussionmentioning

confidence: 99%

Bidirectional solid phase synthesis of a model oligoglycine bolaamphiphile and purification by rapid self‐assembly

Naidoo

Rautenbach

2012

Journal of Peptide Science

View full text Add to dashboard Cite

show abstract

“…In the last years, the struggle to gain innovative and smart materials for industrial and technological applications has widened the field of protein design . By means of supramolecular chemistry, it is now possible to build predictable composites of any desired size and shape . Some of these fully synthetic materials do exhibit the inherent potential of enzyme catalysis.…”

Section: Beyond Protein Cages: Metal‐metalloporphyrin Frameworkmentioning

confidence: 99%

Oxidation catalysis by iron and manganese porphyrins within enzyme‐like cages

et al. 2018

View full text Add to dashboard Cite

Inspired by natural heme-proteins, scientists have attempted for decades to design efficient and selective metalloporphyrin-based oxidation catalysts. Starting from the pioneering work on small molecule mimics in the late 1970s, we have assisted to a tremendous progress in designing cages of different nature and complexity, able to accommodate metalloporphyrins. With the intent of tuning and controlling their reactivity, more and more sophisticated and diverse environments are continuously exploited. In this review, we will survey the current state of art in oxidation catalysis using iron- and manganese-porphyrins housed within designed or engineered protein cages. We will also examine the innovative metal-organic framework (MOF) systems, exploited to achieving an enzyme-like environment around the metalloporphyrin cofactor.

show abstract

“…The bottom-up approach is based on the self-assembly of atoms or molecules toward nanostructures [56]. In other words, the principle of this approach is to make a non-covalent bond art out of covalently bond blocks.…”

Section: Living In the Nanoworldmentioning

confidence: 99%