Bio-Medicus ventricular assist device for salvage of cardiac surgical patients

Killen, Duncan A.; Piehler, Jeffrey M.; Borkon, A. Michael; Reed, William

doi:10.1016/0003-4975(91)91342-s

Cited by 46 publications

(15 citation statements)

References 5 publications

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“…Since 1978, centrifugal blood pumps have become a common device for cardiopulmonary bypass (CPB), and moreover, many trial applications in temporary circulatory support have been done successfully in the United States (1)(2)(3)(4)(5). However, centrifugal pumps are not accepted as ventricular assist devices (VADs) because of their insufficient long-term reliability, which is attributed to a structural defect in the current pump design.…”

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confidence: 99%

Development and Evaluation of Antithrombogenic Centrifugal Pump: The Baylor C–Gyro Pump Eccentric Inlet Port Model

et al. 1994

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The Baylor C-Gyro Pump Eccentric Inlet Port Models (C1E) have been developed aiming for a long-term centrifugal ventricular assist device (VAD) as well as a cardiopulmonary bypass pump. The eccentric inlet port models are characterized by their unique inlet port and secondary impeller vanes. An inlet female pivot bearing, which was fixed to a supporting bar in the prototype model, is directly embedded into the ceiling of the pump casing. An inlet port is then placed off-center to avoid the bearing area, and it is angled between 0 to 90 degrees from the upright position. In addition, small secondary vanes were incorporated into the impeller bottom to accelerate the washout flow behind the impeller. These features attained design objectives proposed for higher antithrombogenicity: a seal-less pump chamber, no stationary parts in the blood path, and acceleration of the secondary flow behind the impeller. The first in vivo experiment using C1E pumps showed excellent antithrombogenicity for up to 18 days when the experiment ceased due to severe infection in the calf.

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confidence: 99%

Development and Evaluation of Antithrombogenic Centrifugal Pump: The Baylor C–Gyro Pump Eccentric Inlet Port Model

et al. 1994

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“…9 Since then, numerous studies have confirmed the efficacy of LHB with a centrifugal pump in postcardiotomy cardiogenic shock.•' The quick and simple set-up, stable circulatory assistance, reliable controllability, and effective LV decompression appear useful in treating postcardiotomy cardiogenic shock, but our results with LHB have not been entirely satisfactory.…”

Section: Discussionmentioning

confidence: 42%

Percutaneous cardiopulmonary support with heparin-coated circuits in postcardiotomy cardiogenic shock

Hayashi

Ohtake

Sawa

et al. 2000

Jpn J Thorac Caridovasc Surg

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“…The effectiveness of currently available centrifugal blood pumps is limited to 2 days because of seal‐related problems (7). The Gyro pump (C1E3) used for this patient has 4 design characteristics: A magnet coupling system and a double pivot bearing system were adopted for driving and supporting the impeller to obtain a completely sealless pump housing, and the inlet port of this pump was placed in an off‐center position to allow the inlet‐side female pivot to be directly embedded into the pump ceiling.…”

Section: Discussionmentioning

confidence: 99%

A Clinical Use of the Kyocera Gyro C1E3 Centrifugal Pump

et al. 2000

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The Kyocera Gyro C1E3 centrifugal blood pump was clinically applied for a cardiopulmonary bypass (CPB) of coronary artery bypass grafting (CABG). The patient was 72-year-old male with postinfarction unstable angina. The surgery was carried out on November 20, 1998. The air inside the pump was easily and quickly removed, and its controllability was excellent. The pump flow during operation was maintained 2.2 L/m2. Total CPB time was 173 min. Perioperative parameters of hemolysis and cytotoxicity were not remarkably changed. Macroscopically and microscopically, there were no thrombi inside the pump after usage. This is the first reported case of clinical use of the Kyocera Gyro C1E3 pump.

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Bio-Medicus ventricular assist device for salvage of cardiac surgical patients

Cited by 46 publications

References 5 publications

Development and Evaluation of Antithrombogenic Centrifugal Pump: The Baylor C–Gyro Pump Eccentric Inlet Port Model

Development and Evaluation of Antithrombogenic Centrifugal Pump: The Baylor C–Gyro Pump Eccentric Inlet Port Model

Percutaneous cardiopulmonary support with heparin-coated circuits in postcardiotomy cardiogenic shock

A Clinical Use of the Kyocera Gyro C1E3 Centrifugal Pump

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