Bioabsorbable Fish Scale for the Internal Fixation of Fracture: A Preliminary Study

Chou, Cheng Hung; Chen, Yong Guei; Lin, Chia‐Her; Lin, Shang; Yang, Kai Chiang; Chang, Shwu Fen

doi:10.1089/ten.tea.2013.0174

Cited by 20 publications

(18 citation statements)

References 45 publications

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“…Cadmium, silicon, yttrium, silver, zinc, copper, magnesium, and trace elements have been used for modifying the HaP properties (Ergun et al, 2002; Cox et al, 2014; Hidouri et al, 2018). Various single ion substitutions in HAp were reported before (Lin and Chang, 2015; Fihri et al, 2017; Kim et al, 2018; Pal et al, 2019).…”

Section: Ceramic Nanoparticlesmentioning

confidence: 92%

Use of Nanoparticles in Tissue Engineering and Regenerative Medicine

Fathi‐Achachelouei

Knopf‐Marques

Silva

et al. 2019

Front. Bioeng. Biotechnol.

290

146

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Advances in nanoparticle (NP) production and demand for control over nanoscale systems have had significant impact on tissue engineering and regenerative medicine (TERM). NPs with low toxicity, contrasting agent properties, tailorable characteristics, targeted/stimuli-response delivery potential, and precise control over behavior (via external stimuli such as magnetic fields) have made it possible their use for improving engineered tissues and overcoming obstacles in TERM. Functional tissue and organ replacements require a high degree of spatial and temporal control over the biological events and also their real-time monitoring. Presentation and local delivery of bioactive (growth factors, chemokines, inhibitors, cytokines, genes etc.) and contrast agents in a controlled manner are important implements to exert control over and monitor the engineered tissues. This need resulted in utilization of NP based systems in tissue engineering scaffolds for delivery of multiple growth factors, for providing contrast for imaging and also for controlling properties of the scaffolds. Depending on the application, materials, as polymers, metals, ceramics and their different composites can be utilized for production of NPs. In this review, we will cover the use of NP systems in TERM and also provide an outlook for future potential use of such systems.

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Section: Ceramic Nanoparticlesmentioning

confidence: 92%

Use of Nanoparticles in Tissue Engineering and Regenerative Medicine

Fathi‐Achachelouei

Knopf‐Marques

Silva

et al. 2019

Front. Bioeng. Biotechnol.

290

146

View full text Add to dashboard Cite

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“…However, the use of mammal collagen may be complicated by an allergic reaction induced in 3-4% of the population [12]. Therefore, fish collagen is being subjected to intensive research with an emphasis on its application for medical purposes [3,[13][14][15][16]. Since fish-derived collagen exhibits a lower melting temperature and less reproducible properties than mammal collagen [17], it must be crosslinked in order to obtain a product that exhibits reproducible properties [14].…”

Section: Introductionmentioning

confidence: 99%

Vancomycin-releasing cross-linked collagen sponges as wound dressings

Hartinger

Mitáš

Mlček

et al. 2019

Bosn J of Basic Med Sci

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The study presents a novel vancomycin-releasing collagen wound dressing derived from Cyprinus carpio collagen type I cross-linked with carbodiimide which retarded the degradation rate and increased the stability of the sponge. Following lyophilization, the dressings were subjected to gamma sterilization. The structure was evaluated via scanning electron microscopy images, micro-computed tomography, and infrared spectrometry. The structural stability and vancomycin release properties were evaluated in a phosphate buffer solution. Microbiological testing and a rat model of a wound infected with methicillin-resistant Staphylococcus aureus (MRSA) were then employed to test the efficacy of the treatment of the infected wound. Following an initial mass loss due to the release of vancomycin, the sponges remained stable. After 7 days of exposure in phosphate buffered saline (37°C), 60% of the material remained with a preserved collagen secondary structure together with a high degree of open porosity (over 80%). The analysis of the release of the vancomycin revealed the homogeneous distribution of the antibiotic both across and between the sponges. The release of vancomycin was retarded as proved by in vitro testing and further confirmed by the animal model from which measurable concentrations were observed in blood samples 24 hours after the subcutaneous implantation of the sponge, which was more than observed following i. p. administration. The sponge was also highly effective in terms of reducing the number of colony-forming units in biopsies extracted from the infected wounds 4 days following the inoculation of the wounds with the MRSA solution.

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“…The main component of fish scale is hydroxyapatite and type-I collagen, which are similar to that of human dentin and bone. Previous studies have characterized the properties of type-I collagen derived from fish scale [ 51 – 53 ], and reported the potential application of as biomaterials in tissue engineering [ 54 – 56 ]. Based on this knowledge, Tang and Saito [ 26 ] investigated the growth, differentiation, mineralization and morphology of MDPC-23 when cultured on tilapia scale collagen (TS collagen).…”

Section: Discussionmentioning

confidence: 99%

Mesenchymal stem cells: A comprehensive methods for odontoblastic induction

et al. 2021

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Background In the area of oral and maxillofacial surgery, regenerative endodontics aims to present alternative options to conventional treatment strategies. With continuous advances in regenerative medicine, the source of cells used for pulp tissue regeneration is not only limited to mesenchymal stem cells as the non-mesenchymal stem cells have shown capabilities too. In this review, we are systematically assessing the recent findings on odontoblastic differentiation induction with scaffold and non-scaffold approaches. Methods A comprehensive search was conducted in Pubmed, and Scopus, and relevant studies published between 2015 and 2020 were selected following the PRISMA guideline. The main inclusion criteria were that articles must be revolving on method for osteoblast differentiation in vitro study. Therefore, in vivo and human or animal clinical studies were excluded. The search outcomes identified all articles containing the word “odontoblast”, “differentiation”, and “mesenchymal stem cell”. Results The literature search identified 99 related studies, but only 11 articles met the inclusion criteria. These include 5 odontoblastic differentiation induction with scaffold, 6 inductions without scaffolds. The data collected were characterised into two main categories: type of cells undergo odontoblastic differentiation, and odontoblastic differentiation techniques using scaffolds or non-scaffold. Conclusion Based on the data analysis, the scaffold-based odontoblastic induction method seems to be a better option compared to the non-scaffold method. In addition of that, the combination of growth factors in scaffold-based methods could possibly enhance the differentiation. Thus, further detailed studies are still required to understand the mechanism and the way to enhance odontoblastic differentiation.

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Bioabsorbable Fish Scale for the Internal Fixation of Fracture: A Preliminary Study

Cited by 20 publications

References 45 publications

Use of Nanoparticles in Tissue Engineering and Regenerative Medicine

Use of Nanoparticles in Tissue Engineering and Regenerative Medicine

Vancomycin-releasing cross-linked collagen sponges as wound dressings

Mesenchymal stem cells: A comprehensive methods for odontoblastic induction

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