Bioactive Compound and Nutritious Characteristic of Bitter Melon Fruit (Momordica Charantia L.)

Abstract

The bitter melon nutritious profile which was full of nutrition all contributed to flexibility towards curing some kind of diseases. The purpose of the research is to investigate nutritious composition of bitter melon (Momordica charantia L.). The parameter used to detect was as follow: ash content, water content, crude protein, crude fat, total carbohydrate, pectin, dietary fiber, calcium, vitamin C, β-carotene, diosgenin, stigmasterol, campesterol and β-sitosterol. The reseach finding showed that the carbohidrate content by different method in the bitter melon was about 60.7-70.90 %. The most dominant dietary fiber content was soluble dietary fiber including19.2-21% pectin as wel as the most dominant phytochemical coumpound was β -sitosterol. Furthermore, crude protein content, crude fat, and ash from fresh bitter melon each was12.8-15.4%; 0.2-0.4%; 11.6-13.4%. Moreover, micro nutritious content such as calcium, vitamin C, and β-carotene each was 676.2-713.4 ppm;119.2-126.2ppm and1.5-1.7 ppm. The existance of indigenous components made the bitter melon having high potential as one of the functional food sources.

The Cytotoxic Effect of Ethanol Extract of Momordica Charantia, Kuguacin-J and Cisplatin on Healthy MCF-10A and MCF-7 and MDAMB-231 Breast Cancer Cell Lines in Vitro

“…However, the underlying mechanisms of the growth inhibitory effects of M charantia extract and K-J in breast cancer cell remains poorly understood. In some cases, more than one processes occur, however, it is known that apoptosis is the dominant type involving the formation of multiprotein complexes that provide the molecular scaffolding for the activation of the initiator caspases including caspase − 8 (extrinsic pathway), caspase − 9 (intrinsic pathway) and caspase − 3 (executioner caspase caspase-3 pathway [25,26,40,41]. The results presented in Fig.…”

“…The results of this study have revealed that M. charantia is rich in a number of cations, especially sodium and calcium, proteins, phenols, antioxidants and other compounds. Other studies have reported more than 250 bioactive compounds with medicinal and nutritious characteristics in M. charantia [41][42][43][44][45]. The question which now arises is: how MC ethanol extract and K-J exerts their lethal effect when applied extracellularly to cells in vitro.…”