Bioactive Peptides from Whey Proteins

Mann, Bimlesh; Athira, S.; Sharma, Rajan; Kumar, Rajesh; Sarkar, Prabin

doi:10.1016/b978-0-12-812124-5.00015-1

Cited by 65 publications

(82 citation statements)

References 131 publications

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“…It contains proteins with a very high biological value, lactose, minerals, and water-soluble vitamins [2,3]. Moreover, it has a number of health-promoting effects [4,5]. e use of whey in food production is one of the most attractive valorisation methods.…”

Section: Introductionmentioning

confidence: 99%

Development of a Novel Whey Date Beverage Fermented with Kefir Grains Using Response Surface Methodology

M’hir

Rtibi

Mejri

et al. 2019

Journal of Chemistry

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The aim of this study was to develop a novel kefir beverage using date syrup, whey permeate, and whey. The levels of the kefir grain inoculum (2–5% w/v), fruit syrup (10–50% w/v), and whey permeate (0–5% w/v) on pH, total phenolic content, antioxidant activity, lactic acid bacteria and yeast counts, and overall acceptability were investigated using central composite design. The use of response surface methodology allowed us to obtain a formulation with acceptable organoleptic properties and high antioxidant activities. The obtained beverages had total phenolic content, % DPPH scavenging activity, and overall acceptability ranging from 24 to 74 mg GAE/mL, from 74.80 to 91.37 mg GAE/mL, and from 3.50 to 6 mg GAE/mL (based on a 1 to 9 preference scale), respectively. Date syrup of 36.76% (w/v), whey permeates of 2.99%, and kefir grains inoculum size of 2.08% were the optimized process conditions achieved.

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Section: Introductionmentioning

confidence: 99%

Development of a Novel Whey Date Beverage Fermented with Kefir Grains Using Response Surface Methodology

M’hir

Rtibi

Mejri

et al. 2019

Journal of Chemistry

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“…Generally, bioactive peptides can be produced by three main ways: by enzymatic hydrolysis with digestive enzymes; by fermentation of milk with proteolytic starter cultures; and by proteolysis with enzymes derived from microorganisms or plants. Also, some studies suggest the combination of these three mentioned models to be effective in generating functional bioactive peptides Mann et al, 2019). Other animal or plant proteins are also a source of bioactive peptides, but milk proteins are the most important and the most abundant source, especially regarding the fact that milk is cost effective and is consumed on everyday basis.…”

Section: Bioactive Peptidesmentioning

confidence: 99%

“…Bioactive peptides act as signalling molecules and thus play an important role in numerous physiological functions and pathogeneses (biological mechanism that leads to diseased state). When bioactive peptide is formed from maternal protein, one of the possible ways to act is being a regulatory compound with hormone-like activity (Mann et al, 2019). Some of physiological effects on human functions that bioactive peptides possess are effect on immune, cardiovascular, nervous and gastrointestinal system ( Figure 2).…”

Section: Bioactive Peptidesmentioning

confidence: 99%

“…Whey presents a rich and heterogeneous mixture of secreted proteins with wide-ranging chemical, show anticancer activity as well as influence to digestive functions. Whey proteins present an essential source of amino acids, but they have also been recognized and classified as dietary proteins which exert many other functions in vivo by means of biologically active peptides (Mann et al, 2019). Milk fermentation using lactic acid bacteria (LAB) or their proteinases has been described as a strategy to release ACE-inhibitory peptides from milk proteins by many authors (Hayes et al, 2006;Mann et al, 2018).…”

Section: Influence Of Bioactive Peptides On Human Healthmentioning

confidence: 99%

“…All κ-casein fragments, known as casoxins behave as opioid antagonists (Severin and Wenshui, 2005). Opioid peptides have also been found encrypted within the primary sequence of whey proteins such as Lf, β-Lg, and bovine serum albumin (Mann et al, 2019).…”

Section: Influence Of Bioactive Peptides On Human Healthmentioning

confidence: 99%

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Bioactive components derived from bovine milk

Barukčić

Božanić

2019

Mljekarstvo.com

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In recent years, functional foods and bioactive components in foods have drawn a lot of attention as well as interest of food scientists, nutritionists, health professionals, and consumers. The advent of this new food category has been facilitated by increasing scientific knowledge about the metabolic and genomic effects of diet and specific dietary components on human health. The relationship between health and diet is well known and it is a main key for prevention of variety of diseases. Milk is considered as a very good source of bioactive components and it has been known to contain macro-as well as micronutrients of high nutritional and therapeutic value. Also, bioactive components have been exploited from milk and dairy products for application in functional foods and for potential pharmaceutical use. Biologically active compounds guard neonates and adults against pathogens and illnesses. Some major bioactive components of milk are derived from caseins, whey proteins, lipids, lactoferrine, vitamins, immunoglobulins and growth factors. The aim of this paper was to provide an overview and explain the health effects of already known and recently detected bioactive components derived from bovine milk on humans.

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