2019
DOI: 10.1016/j.phytol.2019.01.029
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Bioactive secondary metabolites from Plectranthus glandulosus Hook. (Lamiaceae)

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Cited by 10 publications
(8 citation statements)
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“…Moreover, many techniques for isolation, characterization, and pharmacological evaluation have led to an interest in plant secondary metabolites as a source of new drugs, which are potential antimicrobials [42][43][44]. Previous chemical studies of that plant resulted in the isolation of many compounds among which those belonging to the phytochemical classes such as flavonoids are known for their antimicrobial activities [20,42]. In this study, many other known phytochemical compounds have been isolated from P. glandulosus (Figure 1), and their antibacterial activities were evaluated.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Moreover, many techniques for isolation, characterization, and pharmacological evaluation have led to an interest in plant secondary metabolites as a source of new drugs, which are potential antimicrobials [42][43][44]. Previous chemical studies of that plant resulted in the isolation of many compounds among which those belonging to the phytochemical classes such as flavonoids are known for their antimicrobial activities [20,42]. In this study, many other known phytochemical compounds have been isolated from P. glandulosus (Figure 1), and their antibacterial activities were evaluated.…”
Section: Discussionmentioning
confidence: 99%
“…Known as Ava in “Ewondo,” a local tongue in Cameroon, the plant is used as a spice in this part of the country [ 17 ]. Some compounds including one methoxylated flavonoid derivative, plectranmicin, and one monoterpene derivative, plectranmicinol, together with seven known compounds including 5-hydroxy-3,7,2′,4′tetramethoxyflavone; 5,7-dihydroxy-3,2′,4′-trimethoxyflavone; 7-hydroxy-5,6,4′-trimethoxyflavone; 3-epi-betulinic acid; 3- O - β -D-glucopyranosyl; stigmasterol; β -sitosterol, and 4-epi-fridelin were isolated from the whole plant of the studies species [ 20 ]. Earlier biological studies reported the antinociceptive and anti-inflammatory effects [ 21 ] as well as the antioxidant and insecticidal activities of P. glandulosus [ 22 , 23 ].…”
Section: Introductionmentioning
confidence: 99%
“… ∗ The different flavonoids have the same m/z. The assignments were done in comparison with the literature [ 32 , 33 ]. …”
Section: Figurementioning
confidence: 99%
“…Phytochemical examination of P. glandulosus revealed the presence of secondary metabolites such as alkaloids, flavonoids, saponins, terpenoids, steroids, tannins, and glucosides [ 28 – 31 ]. Further phytochemical studies isolated a methoxylated flavonoid derivative plectranmicin, a monoterpene derivative plectranmicinol, and seven known compounds (5-hydroxy-3,7,2′,4′-tetramethoxyflavone, 5,7-dihydroxy-3,2′,4′-trimethoxyflavone, 7-hydroxy-5,6,4′-trimethoxyflavonen, 3-epi-betulinic acid, 3 -O-β -D-glucopyranosyl stigmasterol, β -sitosterol, and 4-epi-fridelin) [ 32 ]. Nanmeni et al [ 33 ] isolated seventeen compounds form de ethanolic whole plant extract including the mixture of stigmasterol and β -sitosterol, oleanolic acid, pilloin, β -sitosterol 3- O - β -D-glucopyranoside, chrysoeriol, luteolin 7-methyl ether, 5-hydroxy-7,4′-dimethoxyflavone, mixture of maslinic acid and benthamic acid, 5,6-dihydroxy-7,3′,4′-trimethoxyflavone, ladanein, hederagenin, cylicodiscic acid, mixture of chrysoeriol 5- O - β -D-glucopyranoside and 7- O -methyl luteolin 5- O - β -D-glucopyranoside, and galuteolin.…”
Section: Introductionmentioning
confidence: 99%
“…Earlier studies reported the antinociceptive and anti-inflammatory effects 13 as well as antioxidant and insecticidals activities 14,15,16 . As phytochemical constituents of P. glandulosus, one new methoxylated flavonoid derivative, plectranmicin and one new monoterpene derivative, plectranmicinol, together with seven known compounds including 5-hydroxy-3,7,2′,4′tetramethoxyflavone; 5,7-dihydroxy-3,2′,4′trimethoxyflavone; 7-hydroxy-5,6,4′trimethoxyflavonen; 3epi-betulinicacidn; 3O-β-D-glucopyranosylstigmasterol; βsitosterol and 4-epi-fridelin were isolated from the whole plant 17 .…”
Section: Introductionmentioning
confidence: 99%