Bioadhesive liquid crystal systems for octyl methoxycinnamate skin delivery

Prado, Alice Haddad do; Duarte, Jonatas Lobato; Filippo, Leonardo Delello Di; Victorelli, Francesca Damiani; Fantini, Márcia Carvalho de Abreu; Peccinini, Rosângela Gonaçalves; Chorilli, Marlus

doi:10.1016/j.molliq.2021.117450

Cited by 8 publications

(2 citation statements)

References 64 publications

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“…Both of these organic filters are extensively employed in photoprotective formulations due to their ability to absorb a broad spectrum of UV radiation absorption, encompassing both UVA and UVB rays, especially when combined [76]. Despite the OMC effectiveness, studies have indicated its penetration into deeper layers of the skin, including the dermis and adipose tissue, with systemic absorption evidenced by its presence in urine and milk samples following topical application [77]. Conversely, BMBM demonstrates high efficacy against the UVA radiation spectrum, yet its photostability is compromised, impacting its effectiveness in photoprotective formulations.…”

Section: Liposomes As a Strategy For Ulraviolet Filter Deliverymentioning

confidence: 99%

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Miranda,

Cruz,

Girão

et al. 2024

Pharmaceutics

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Sunscreen products are essential for shielding the skin from ultraviolet (UV) radiation, a leading cause of skin cancer. While existing products serve this purpose, there is a growing need to enhance their efficacy while minimizing potential systemic absorption of UV filters and associated toxicological risks. Liposomal-based formulations have emerged as a promising approach to address these challenges and develop advanced photoprotective products. These vesicular systems offer versatility in carrying both hydrophilic and lipophilic UV filters, enabling the creation of broad-spectrum sunscreens. Moreover, their composition based on phospholipids, resembling that of the stratum corneum, facilitates adherence to the skin’s surface layers, thereby improving photoprotective efficacy. The research discussed in this review underscores the significant advantages of liposomes in photoprotection, including their ability to limit the systemic absorption of UV filters, enhance formulation stability, and augment photoprotective effects. However, despite these benefits, there remains a notable gap between the potential of liposomal systems and their utilization in sunscreen development. Consequently, this review emphasizes the importance of leveraging liposomes and related vesicular systems as innovative tools for crafting novel and more efficient photoprotective formulations.

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Section: Liposomes As a Strategy For Ulraviolet Filter Deliverymentioning

confidence: 99%

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Miranda,

Cruz,

Girão

et al. 2024

Pharmaceutics

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“…By taking advantage of the selective reflection properties of CLC, it can be used to make infrared reflectors 17 and direct writing inks 18 . The connection between LC and sunscreen is that LC is generally used as a surfactant in sunscreen 19,20 . Heemuk Oh et al 21 prepared cholesteric liquid crystal (CLC) microcapsules as sunscreen, which could reduce the UV in the range of 290–400 nm by 6%, but they used only one‐handed CLC microcapsules, which caused the microcapsules to lack a blocking effect on the other kind of handed UV 22 …”

Section: Introductionmentioning

confidence: 99%

Excellent ultraviolet‐blocking properties of chiral nematic liquid crystals

Wang

Zhang

et al. 2023

Photochem & Photobiology

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We report the evaluation of chiral nematic liquid crystal (CNLC) in blocking ultraviolet (UV). The CNLC was coated on a calcium fluoride substrate to measure the spectral transmittance, which was measured to detect the UV‐blocking effect of CNLC. The results show that CNLC could reduce UVB (290–320 nm) by 99.9% and UVA (320–400 nm) by 95.6%. The barrier effect of cake‐shaped semi‐solidified CNLC microspheres was further investigated, and it was found that cake‐shaped semi‐solidified CNLC microspheres could reduce UVB by 58.2% and UVA by 34.1%. This is due to the chemical absorption property of CNLC, which has UV‐absorbing functional groups such as the benzene rings. And the physical reflection properties of CNLC could periodically reflect a certain wavelength of light. Liquid crystal (LC) is a rich set of soft materials with rod‐like structures widely existing in nature, which is harmless to the human body and environment. Therefore, using CNLC's function of blocking UV, a new sunscreen can be developed.

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Self-assembled lyotropic liquid crystals gel systems for retinol protection and octyl methoxycinnamate skin delivery

Zan,

Lin,

et al. 2023

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Bioadhesive liquid crystal systems for octyl methoxycinnamate skin delivery

Cited by 8 publications

References 64 publications

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Excellent ultraviolet‐blocking properties of chiral nematic liquid crystals

Self-assembled lyotropic liquid crystals gel systems for retinol protection and octyl methoxycinnamate skin delivery

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