2016
DOI: 10.18282/jsd.v2.i1.64
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Biochemical pathways and targeted therapies in basal cell carcinoma: A systematic review

Abstract: Basal cell carcinoma (BCC) is the most common type of human malignancy. It is a slow-growing skin cancer with little ability to metastasize, but it is aggressive and can cause local tissue destruction. Descriptions of Basal Cell Nevus Syndrome (BCNS), characterized by a predisposition to the formation of BCC and other neoplasms, and identification of the genetic defect in this syndrome, has led to significant advancement in our understanding of the pathogenesis of BCC. Unregulated expression of target genes in… Show more

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Cited by 2 publications
(1 citation statement)
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“…Apart from being a life-threatening disease, cancer poses a great burden on the finances of the family. The drugs are exorbitantly costly (no generic anti-cancer drugs are available) and adjuvant procedures such as bone marrow transplant, surgeries and hormonal therapy are even more costly [5] . However, despite of difficulties that cancer patients face, very few hospitals provide quality care at low price to such patients -often with the help of non-governmental organizations.…”
Section: Cancer Financing -A Challenge For Healthcare Financing In Indiamentioning
confidence: 99%
“…Apart from being a life-threatening disease, cancer poses a great burden on the finances of the family. The drugs are exorbitantly costly (no generic anti-cancer drugs are available) and adjuvant procedures such as bone marrow transplant, surgeries and hormonal therapy are even more costly [5] . However, despite of difficulties that cancer patients face, very few hospitals provide quality care at low price to such patients -often with the help of non-governmental organizations.…”
Section: Cancer Financing -A Challenge For Healthcare Financing In Indiamentioning
confidence: 99%