2024
DOI: 10.1002/advs.202403615
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Biocompatible Liquid Embolic for the Treatment of Microvascular Hemorrhage

Hyeongseop Keum,
Jinjoo Kim,
Zefu Zhang
et al.

Abstract: Persistent or recurrent bleeding from microvessels inaccessible for direct endovascular intervention is a major problem in medicine today. Here, an innovative catheter‐directed liquid embolic (P‐LE) is bioengineered for rapid microvessel embolization to treat small vessel hemorrhage. Tested in rodent, porcine, and canine animal models under normal and coagulopathic conditions, P‐LE outperformed clinically used embolic materials in both survival and non‐survival experiments, effectively occluding vessels as sma… Show more

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