Biocompatible superhydrophobic coating material for biomedical applications

Mahadik, Satish A.; Pedraza, F.; Mahadik, Sarika S.; Relekar, B. P.; Thorat, Sagar S.

doi:10.1007/s10971-016-4244-4

Cited by 22 publications

(8 citation statements)

References 32 publications

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“…However, nano SiO 2 is most extensively studied for fabrication of superhydrophobic surfaces. Recent report shows that functionalised SiO 2 -based superhydrophobic coatings have significant bactericidal activities [15,18]. Not only inorganic material-based nanomaterials but also organic materials like chitosan nanoparticles are known for their biocompatibility, biodegradability and widespread antibacterial and antifungal activities towards the fabrication of superhydrophobic and antimicrobial coatings on cotton fabrics [8].…”

Section: Nanomaterials As Antimicrobial Agentsmentioning

confidence: 99%

“…Reduced graphene oxide-based nanomaterials have been used for fabrication of antimicrobial and superhydrophobic coatings with excellent mechanical strength and corrosion resistance property [10][11][12][13]. It is worthy to note that superhydrophobic and antimicrobial surfaces have found applications in medical textiles [14], military clothing [2], anti-biofouling coatings on surgical appliances and biodevices [15].…”

Section: Nanomaterials As Antimicrobial Agentsmentioning

confidence: 99%

“…Among these, metal and metal oxide-based nanomaterials such as Ag [3], Cu 15],chemical reduction [4], spray coating technique [6,8], electroplating method [16], template method [17] and so on. In the later stage, the hierarchical rough surface is to be modified by using a low energy material adopting various techniques including layer by layer deposition [3], solution process [2,4,6,15], chemisorption [18], and self-assembly [14]. The existence of trapped air in the rough surface that created due to the presence of micro and nanostructures impede water droplets to come in contact with the substrate surface and it is one of the key factors for obtaining antimicrobial activity of a nanomaterial based superhydrophobic surface.…”

Section: Introductionmentioning

confidence: 99%

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Nanomaterials Based Superhydrophobic and Antimicrobial Coatings

Seth¹,

Jana²

2020

NanoWorld J

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Now-a-days, it is obvious that nanomaterials can play significant role in every sphere of our modern lives. On this aspect, use of nanomaterials in developing advanced functional materials or towards enhancement in surface related physical properties including superhydrophobic or superhydrophilic properties is very important both in fundamental and applied research. In this regard, most of the researchers agreed that there is a close relationship between superhydrophobicity of material surface with its antimicrobial activity. This review briefly highlights the use of some inorganic/organic based nanomaterials such as Ag, Cu, ZnO, TiO 2 as inorganic materials and graphene, chitosan nanoparticles as organic materials in making superhydrophobic antimicrobial coatings. Based on reported literature, possible mechanisms of antimicrobial activity of the nanomaterials derived superhydrophobic coatings have been discussed. It is worthy to note that the coatings with the advancement in self-cleaning and anti-biofouling as well as superhydrophobic and antimicrobial properties are highly potential for enormous applications in biomedical fields including medical textiles, personal protective equipment (PPE), surgical appliances, biodevices and so on. In this review, the challenges and future prospect of the nanomaterials based superhydrophobic coatings have also been discussed briefly. This mini review may encourage researchers towards development of superhydrophobic and antimicrobial coatings on various substrates like plastics, glasses, cotton fabrics for making PPE to protect the dedicated medical / healthcare personnel from the currently pandemic COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2.

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Section: Nanomaterials As Antimicrobial Agentsmentioning

confidence: 99%

Section: Nanomaterials As Antimicrobial Agentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Nanomaterials Based Superhydrophobic and Antimicrobial Coatings

Seth¹,

Jana²

2020

NanoWorld J

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“…Therefore, the extraction of SiO 2 from POFA via methods such as acid leaching [ 5 ], alkaline leaching [ 6 ], and sol-gel method [ 7 ] for utilization as super-hydrophobic coating alleviates the environmental burden brought about by the healthcare and agricultural industry. The super-hydrophobic coating can be successfully utilized for medical implants, contact lenses, controlled drug delivery and diagnostic applications [ 9 , 10 ]. The super-hydrophobicity of the material is primarily utilized to prevent the attachment of microorganisms on the biomedical device’s surface.…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility and Cytotoxicity Study of Polydimethylsiloxane (PDMS) and Palm Oil Fuel Ash (POFA) Sustainable Super-Hydrophobic Coating for Biomedical Applications

et al. 2020

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A sustainable super-hydrophobic coating composed of silica from palm oil fuel ash (POFA) and polydimethylsiloxane (PDMS) was synthesised using isopropanol as a solvent and coated on a glass substrate. FESEM and AFM analyses were conducted to study the surface morphology of the coating. The super-hydrophobicity of the material was validated through goniometry, which showed a water contact angle of 151°. Cytotoxicity studies were conducted by assessing the cell viability and cell morphology of mouse fibroblast cell line (L929) and hamster lung fibroblast cell line (V79) via tetrazolium salt 3-(4–dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and microscopic methods, respectively. The clonogenic assay was performed on cell line V79 and the cell proliferation assay was performed on cell line L929. Both results validate that the toxicity of PDMS: SS coatings is dependent on the concentration of the super-hydrophobic coating. The results also indicate that concentrations above 12.5 mg/mL invariably leads to cell toxicity. These results conclusively support the possible utilisation of the synthesised super-hydrophobic coating for biomedical applications.

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“…PDMS is a soft polymer with attractive chemical and physical properties such as biocompatibility, low toxicity, flexible surface chemistry, low permeability to water, elastomeric properties, ease of fabrication and use, as well as low manufacturing costs [ 2 ]. It is widely used to reduce or prevent bioadhesion in biomedical field [ 3 , 4 , 5 , 6 , 7 , 8 ]. However, these kinds of coatings are prone to protein adsorption and accumulation of strongly adherent diatom slimes [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Non-Leachable Hydrophilic Additives for Amphiphilic Coatings

et al. 2018

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Amphiphilic surfaces are particularly effective at inhibiting the adhesion of microorganisms (bacteria, cells, microalgae, etc.) in liquid media. The aim of this study is to determine the best hydrophilic linker to promote bonding between poly(ethylene glycol) (PEG) as a hydrophilic additive and poly(dimethyl siloxane) (PDMS) as the hydrophobic matrix. Various parameters have been studied (molecular weight, linker type, and polymer end-group), as well as the efficiency of the linking, the capacity of PEG to access to the surface of the film, and overall film homogeneity. According to the results, a PDMS linker paired with a PEG moiety allows for compatibilization of the compounds during cross-linking. This compatibilization seems to provide a good bonding with the matrix and a good surface access to the hydrophilic moiety. Therefore, this structure comprising a linking function attached to the PDMS–PEG copolymer has high potential as a non-releasable additive for amphiphilic coating applications.

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Biocompatible superhydrophobic coating material for biomedical applications

Cited by 22 publications

References 32 publications

Nanomaterials Based Superhydrophobic and Antimicrobial Coatings

Nanomaterials Based Superhydrophobic and Antimicrobial Coatings

Biocompatibility and Cytotoxicity Study of Polydimethylsiloxane (PDMS) and Palm Oil Fuel Ash (POFA) Sustainable Super-Hydrophobic Coating for Biomedical Applications

Non-Leachable Hydrophilic Additives for Amphiphilic Coatings

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