Biodegradable polypyrrole/dextrin conductive nanocomposite: Synthesis, characterization, antioxidant and antibacterial activity

Zare‬, Ehsan Nazarzadeh; Lakouraj, Moslem Mansour; Mohseni, Mojtaba

doi:10.1016/j.synthmet.2013.09.045

Cited by 153 publications

(41 citation statements)

References 50 publications

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“…Antimicrobial polysaccharides are usually natural polymer or its derivatives such as starch and CS, which are being recently used for the preparation of hydrogels because of their nontoxicity, biodegradability, biocompatibility and abundance in nature. 271,272 Some of these polysaccharides have inherent antimicrobial activity, the most popular one is CS. CS has wide antibacterial spectrum of activity and high killing rate against Gram-positive and Gram-negative bacteria and low toxicity toward mammalian cells.…”

Section: Antimicrobial Polysaccharidesmentioning

confidence: 99%

Antimicrobial hydrogels: promising materials for medical application

Yang

Han

Chen

et al. 2018

IJN

317

230

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The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an imminent global public health problem. Local application of antibiotics might be a solution. In local application, materials need to act as the drug delivery system. The drug delivery system should be biodegradable and prolonged antibacterial effect should be provided to satisfy clinical demand. Hydrogel is a promising material for local antibacterial application. Hydrogel refers to a kind of biomaterial synthesized by a water-soluble natural polymer or a synthesized polymer, which turns into gel according to the change in different signals such as temperature, ionic strength, pH, ultraviolet exposure etc. Because of its high hydrophilicity, unique three-dimensional network, fine biocompatibility and cell adhesion, hydrogel is one of the suitable biomaterials for drug delivery in antimicrobial areas. In this review, studies from the past 5 years were reviewed, and several types of antimicrobial hydrogels according to different ingredients, different preparations, different antimicrobial mechanisms, different antimicrobial agents they contained and different applications, were summarized. The hydrogels loaded with metal nanoparticles as a potential method to solve antibiotic resistance were highlighted. Finally, future prospects of development and application of antimicrobial hydrogels are suggested.

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Section: Antimicrobial Polysaccharidesmentioning

confidence: 99%

Antimicrobial hydrogels: promising materials for medical application

Yang

Han

Chen

et al. 2018

IJN

317

230

View full text Add to dashboard Cite

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“…The COC vibration region of 950–1,500 cm −1 includes bands at 1170 cm −1 , ascribed to the asymmetric stretching of glycosidic COC bridge; 1,120 cm −1 , associated to the alcoholic CH 2 OH stretching mode; and 1,076 cm −1 , ascribed to COH twisting vibrations. Finally, bands at 930 and 774 cm −1 are due to ring stretching and deformation modes of the (α‐1,4) and (α‐1,6) linkages . The FTIR spectrum of PEO fibers (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…It consists of α‐D‐glucopyranose units arranged in a core cyclic chain and branched side chains, where (α‐1,6) linkages act as branching points on the (α‐1,4)‐linked chains. Its biocompatibility, biodegradability, and nonimmunogenic nature make of dextrin a good candidate for the fabrication of antioxidant and antibacterial fiber scaffolds for tissue engineering with the potential of combining topical drug delivery applications for skin wound healing.…”

Section: Introductionmentioning

confidence: 99%

Characterization of mechanically reinforced electrospun dextrin‐polyethylene oxide sub‐microfiber mats

Rodríguez‐Zamora

Peña‐Juárez

Cedillo‐Servín

et al. 2019

Polymer Engineering & Sci

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Dextrin and dextrin‐polyethylene oxide (DEX/PEO) fibers in the submicron range were produced by electrospinning of single and blend polymer solutions. The morphology, intermolecular interactions, and mechanical properties of dextrin microfibers with and without PEO were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, X‐ray diffraction, nuclear magnetic resonance spectroscopy, and uniaxial tensile testing. Spectroscopic results confirmed hydrogen bond formation, evidencing dextrin as a molecular entanglement source for fiber mechanical reinforcement. The uniaxial tensile tests demonstrated a synergistic mechanical reinforcement effect that varied with blend composition. Equal weight ratio blends supported a maximum tensile strength with a high elastic modulus and demonstrated to be more elastic and resistant to breaking, even than pristine PEO fibers. Moreover, elastic moduli of blend fiber mats were found to lie within the value range for human skin, thus providing the DEX/PEO meshes with potential applicability as skin tissue scaffolds. This synthesis approach proved the feasible and inexpensive fabrication process of natural‐synthetic polymer hybrid fibers that combine the biocompatibility, biodegradability, and encapsulating capability of dextrin with the mechanical strength and flexibility of PEO for the development of scaffolds for tissue engineering and topical drug delivery applications in skin wound healing. POLYM. ENG. SCI., 59:1778–1786, 2019. © 2019 Society of Plastics Engineers

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“…导电材料可以提高成纤维细胞和角质细胞活性, 这两种细胞在皮肤愈合过程中发挥着重要的作用 [50] . 此外, 导电聚合物(如PANi)还显示出良好的抗菌能力 [94] , 具有促进皮肤愈合的潜力 [72,95] . 本课题组…”

Section: 支架的取向结构可以模拟骨骼肌中肌纤维的各向异性结构研究发现由取向的纳米纤维组成的静电纺丝支unclassified