Biodegradation of chlorinated dibenzo-p-dioxins in batch and continuous cultures of strain JB1

Parsons, John R.; Storms, M.C.M.

doi:10.1016/0045-6535(89)90077-5

Cited by 37 publications

(14 citation statements)

References 12 publications

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“…In fact, the 1,2-dihydroxylated derivatives appear to inhibit the ring cleavage enzymes in this strain. The biphenyl-utilizing Alcaligenes strain JB1 appears to co-metabolize mono-, di-and trichlorinated dioxins by the same mechanism (Parsons & Storms 1989).…”

Section: Degradation Of Halogenated Dibenzo-p-dioxins and Dibenzofuransmentioning

confidence: 99%

Degradation of halogenated aromatic compounds

1990

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Due to their persistence, haloaromatics are compounds of environmental concern. Aerobically, bacteria degrade these compounds by mono- or dioxygenation of the aromatic ring. The common intermediate of these reactions is (halo)catechol. Halocatechol is cleaved either intradiol (ortho-cleavage) or extradiol (meta-cleavage). In contrast to ortho-cleavage, meta-cleavage of halocatechols yields toxic metabolites. Dehalogenation may occur fortuitously during oxygenation. Specific dehalogenation of aromatic compounds is performed by hydroxylases, in which the halo-substituent is replaced by a hydroxyl group. During reductive dehalogenation, haloaromatic compounds may act as electron-acceptors. Herewith, the halosubstituent is replaced by a hydrogen atom.

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Section: Degradation Of Halogenated Dibenzo-p-dioxins and Dibenzofuransmentioning

confidence: 99%

Degradation of halogenated aromatic compounds

1990

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“…The biphenyl-utilizing bacterium Burkholderia sp. strain JB1, formerly classified as Alcaligens sp., degraded 2-MCDD, although this organism failed to grow with this compound 145) . Continuous exposure of strain JB1 to a mixture of chlorinated DDs resulted in degradation of 1,3-and 2,8-DCDDs and 1,2,4-TrCDD.…”

Section: Biodegradation Of Chlorinated Congenersmentioning

confidence: 99%

Biodiversity of Dioxin-Degrading Microorganisms and Potential Utilization in Bioremediation.

Hiraishi

2003

Microb. Environ.

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Dioxins are a group of chloroaromatic compounds known to be toxic and carcinogenic, and persistent environmental pollutants. How to remedy dioxin-polluted environments is one of the most challenging problems in environmental technology. From ecological and economical viewpoints, biological methods using particular microorganisms and microbial consortia capable of dioxin transformation and degradation have greater appeal than physicochemical methods in their application for environmental remediation. Large numbers of microorganisms capable of degrading dioxins and dioxin-like compounds have been isolated and characterized. Information about the biodiversity, ecophysiology and molecular biology of dioxin-degrading microorganisms has accumulated particularly during the past decade. There are three major modes of microbial degradation and transformation of dioxins; that is, oxidative degradation by aerobic bacteria containing aromatic hydrocarbon dioxygenases, reductive dechlorination by anaerobic microorganisms and fungal oxidation with cytochrome P-450, lignin peroxidases and laccases. This article overviews the current knowledge of microbial degradation and transformation of dioxins as well as the biodiversity of microorganisms involved. Strategies directed towards the bioremediation of dioxin-polluted environments are discussed.

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“…After one month exposure of rainbow trout to food contaminated with 9 pg kg -~ 2,3,4,7,8-PnCDF, ethoxyresorufin-O-deethylase (EROD) activity remained at an increased level for 180 days . Congeners with few chlorine atoms are biodegradable under certain conditions (Parsons and Storms, 1989), but a number of the tetra-and higherchlorinated congeners are persistent in the environment. Furthermore, dioxins and furans are extremely hydrophobic compounds that readily associate with organic materials when entering the aquatic environment, resulting in high sediment concentrations (Karickhoff et al, 1979).…”

Section: Introductionmentioning

confidence: 99%

Bioconcentration of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in guppies after aqueous exposure to a complex PCDD/PCDF mixture: relationship with molecular structure

et al. 1994

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Bioconcentration of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in guppies after aqueous exposure to a complex PCDD/PCDF mixture: relationship with molecular structure. Loonen, H.E.W.M.; Tonkes, M.; Parsons, J.R.; Govers, H.A.J. Disclaimer/Complaints regulationsIf you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. AbstractGuppies (Poecilia reticulata) were exposed to a complex mixture of polychlorinated dibenzop-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in water for 21 days. It is the first study in which accumulation data of 15 toxic dioxins and furans were quantified simultaneously in a continuous exposure experiment. First-order uptake rate constants (kl) and firstorder elimination rate constants (k2) were calculated for the toxic, laterally substituted congeners. Bioconcentration factors (BCFs) were calculated from both the ratios of concentrations in fish and water and from the ratios of the rate constants. Dioxins and furans were selectively accumulated in fish tissue. The non-laterally substituted congeners were either not observed in fish tissue or showed lower BCF values than their laterally 2,3,7,8-substituted isomers. The log BCF values of laterally substituted congeners ranged from 3.90 + 0.06 to 5.27 + 0.07. BCF values were smaller than predicted by existing linear relationships with log Kow. Several phenomena were discussed with respect to the observed bioconcentration behaviour, such as limited bioavailability, reduced lipid solubility, reduced membrane permeability and biotransformation. Furthermore, the similarity between structure-activity relationships considering bioaccumulation in fishes and the Ah-affinity in mammals was discussed.

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Biodegradation of chlorinated dibenzo-p-dioxins in batch and continuous cultures of strain JB1

Cited by 37 publications

References 12 publications

Degradation of halogenated aromatic compounds

Degradation of halogenated aromatic compounds

Biodiversity of Dioxin-Degrading Microorganisms and Potential Utilization in Bioremediation.

Bioconcentration of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in guppies after aqueous exposure to a complex PCDD/PCDF mixture: relationship with molecular structure

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