“…All the studies included in this systematic review were eleven In-vitro studies 8,10,12,13,20,26,[28][29][30][31][32] , two In-vivo studies 2,17 , one Randomized controlled trial study (RCT) 33 , four Retrospective clinical studies 18,[34][35][36] , and four Case reports. 1,7,9,37 In regard to the types of root repair materials performed, fourteen studies were performed with MTA in a combination of other root repair materials such as ERRM and Biodentine. 2,8,10,12,13,17,20,26,[28][29][30][31][32]35 The placement of Biodentine alone as a root repair material for root perforation was made in three studies.…”