BiodentineTM versus formocresol pulpotomy technique in primary molars: a 12–month randomized controlled clinical trial

Meligy, Omar El; Alamoudi, Najlaa M.; Allazzam, Sulaiman Mohamed; El‐Housseiny, Azza A.

doi:10.1186/s12903-018-0702-4

Cited by 44 publications

(50 citation statements)

References 26 publications

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“…In this study, the high clinical outcome of FC agree with the success rate of FC reported by other investigators (47,52,53) , but it is not in agreement with the outcomes of other studies (54,55) .…”

Section: Discussionsupporting

confidence: 55%

“…Our results revealed a 100% clinical success rate for both groups. This may be attributed to correct protocol, careful diagnosis with complete tooth isolation, and proper manipulation of the material under aseptic conditions (47) . Although a rare number of publications in the literature reporting on amnion pulpotomy, consistent with our survey, this outcome agrees with the study of Prasad et al (36) who reported 100% clinical success for both groups.…”

Section: Discussionmentioning

confidence: 99%

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Clinical, Radiographical and Histopathological Evaluation of Amniotic Membrane Allograft Pulpotomy in Primary teeth

Beltagy

Yasser

2019

Egyptian Dental Journal

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Background: A novel dehydrated Human Amniotic Membrane (dHAM) allograft is a placental based scaffold that has been widely used in a verity of medical fields due to its unique regenerative ability in wound healing. Objective: To evaluate clinically, radiographically, and histopathologically the efficacy of dehydrated Human Amniotic Membrane allograf as a pulpotomy agent in primary teeth. Materials and Methods: I-Clinical and radiographical evaluation: This split-mouth, randomized clinical trial was conducted on 40 deeply carious primary molars indicated for pulpotomy. They were selected from 16 healthy children aged 4-8 years. They were randomly allocated into two equal groups (20 molars/each). Group 1: dHAM pulpotomy in one quadrant and Group 2: Formocresol (FC) pulpotomy in the contralateral. All molars were treated with the conventional pulpotomy technique. All patients were recalled for clinical and radiographical evaluation at 3, 6, and 9 months post-treatment. II-Histopathological assessment: A total of 30 healthy lower first primary molars and canines that indicated for serial extraction were selected for histopathological evaluation. The dHAM allograft and formocresol pulpotomies were performed (12 teeth/each group), where the other 6 teeth were used as a control. Six teeth from each experimental group were extracted at post-treatment intervals; one and three months. The samples were prepared for histopathological evaluation. All data were subjected to the exact test. Fisher exact test and Monte Carlo test were also used. The level of significance was set at P<0.05. Results: I-Clinical and radiographic results: The overall clinical success rates for both groups were 100%, whereas the overall radiographic success rates for dHAM and FC groups were 100% and 85%, respectively, but the difference was not statistically significant (p>0.05). II-Histopathological results: The overall evaluation at 1-month interval showed better histopathological criteria for dHAM group than FC group, but the difference was only significantly better on the degree of the inflammatory response (p<0.05). Whereas at 3-month interval, the dHAM group displayed significantly better histopathological criteria compared to the FC group (p<0.05). Conclusion: The dHAM allograft with its regenerative, biologic biocompatibility properties and its ability to deliver growth factors has shown successful outcome comparable to gold standard formocresol. Hence, it can be recommended as an alternative promising pulpotomy agent.

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Section: Discussionsupporting

confidence: 55%

Section: Discussionmentioning

confidence: 99%

Clinical, Radiographical and Histopathological Evaluation of Amniotic Membrane Allograft Pulpotomy in Primary teeth

Beltagy

Yasser

2019

Egyptian Dental Journal

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“…On the other hand, the comparison between FC and MTA [55,66,67,70,72,[76][77][78]85,86,88,90], yielded a better performance of the latter after 12, 24, 30 and 42 months of evaluation. Accordingly, El Meligy et al [87] observed slightly favorable clinical and radiographical outcomes of primary teeth underwent pulpotomy performed with BD than FC, although no statistically significant.…”

Section: Discussionmentioning

confidence: 97%

“…El Meligy et al [87] clinically and radiographically evaluated 108 primary teeth that underwent pulpotomy performed with BD or FC. After 12 months, the authors reported a 100% clinical success rate in both groups and a radiographic success rate of 100% and 98.1% in the BD and FC groups, respectively, although without any statistically significant difference.…”

Section: Biodentinementioning

confidence: 99%

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Bossù

Iaculli

Giorgio

et al. 2020

JCM

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Background: Pulpotomy of primary teeth provides favorable clinical results over time; however, to date, there is still not a consensus on an ideal pulp dressing material. Therefore, the aim of the present systematic review was to compare pulpotomy agents to establish a preferred material to use. Methods: After raising a PICO question, the PRISMA guideline was adopted to carry out an electronic search through the MEDLINE database to identify comparative studies on several pulp dressing agents, published up to October 2019. Results: The search resulted in 4274 records; after exclusion, a total of 41 papers were included in the present review. Mineral trioxide aggregate (MTA), Biodentine and ferric sulphate yielded good clinical results over time and might be safely used in the pulpotomies of primary molars. Among agents, MTA seemed to be the material of choice. On the contrary, calcium hydroxide showed the worst clinical performance. Although clinically successful, formocreosol should be replaced by other materials, due to its potential cytotoxicity and carcinogenicity. Conclusion: MTA seemed to be the gold standard material in the pulpotomy of primary teeth. Promising results were also provided by calcium silicate-based cements. Further randomized clinical trials (RCTs) with adequate sample sizes and long follow-ups are encouraged to support these outcomes. deciduous or young permanent teeth with immature roots affected by caries and without evidence of radicular pathology [7,8]. Nowadays, treatment options of VPT are represented by indirect pulp treatment (namely indirect pulp capping), direct pulp capping and pulpotomy [7]. Although clinically successful in primary molars, direct capping is mainly recommended in the VPT of permanent young teeth [9,10] and indirect capping seems to possess a relative effectiveness when compared to pulpotomy procedures [11]. The latter provides favorable clinical survival rates over time and allows the vitality of primary teeth until their natural exfoliation, avoiding pulpectomy procedures [2]. Pulpotomy consists of elimination of the bacterial infection by the removal of the pulp in the pulp chamber; then, the decontaminated tooth is filled with a medicament [11]. The most frequently used agents are mineral trioxide aggregate (MTA), Biodentine (BD), formocresol (FC), ferric sulphate (FS) and calcium hydroxide (CH). When compared, FC, FS and MTA seemed to provide significantly better clinical and radiographic results as pulpotomy agents than CH after two years of follow-up; moreover, MTA showed the best performance in respect to FC and FS over time [12]. Accordingly, Stringhini et al. [13] reported that MTA yielded superior clinical and radiographical results in comparison to FC. On the other hand, electrosurgery and FS showed similar success to FC, whereas CH did not show positive evidence as medicament in pulpotomies of primary teeth [13]. In the same way, Asgary et al. [14] further stressed that MTA demonstrated better long-term outcomes in pulpotomy of primary molars when com...

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“…Com o advento da tecnologia e inovação, muitos materiais capeadores estão sendo desenvolvidos e estudados para reparo e regeneração do tecido pulpar vital (Kuzum et al, 2015;Hugar et al, 2017;Kalra et al, 2017;Gopalakrishnan et al, 2019;Çelik et al, 2019;El Meligy et al, 2019 (Marques et al, 2014;Fernandes et al, 2015;Lourenço Neto et al, 2015;Lourenço Neto et al, 2016). (Marques et al, 2014;Fernandes et al, 2015;Lourenço Neto et al, 2015;Lourenço Neto et al, 2016 (Marques et al, 2014;Fernandes et al, 2015;Lourenço Neto et al, 2015;Lourenço-Neto et al, 2016).…”

Section: Introductionunclassified

Alternativas de terapia pulpar vital para reparo do complexo dentino/pulpar de dentes decíduos

Stafuzza¹

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Alternatives for vital pulp therapy for dentin-pulp complex repair of primary teeth This thesis aimed to present two scientific papers. In the Article 1, the objective was to evaluate the knowledge of students and professionals on selective caries tissue removal and in Article 2, the objective will be to present the protocol of a new dentinpulp biostimulation material. In the Article 1, the sample included students from the 3rd and 4th year of a Dental School (Group 1) and professionals from a Hospital Dental Center (Group 2). An anonymous, confidential, validated, and translated questionnaire containing eleven questions including questions about therapeutic attitudes, diagnosis, and behavior towards deep carious lesions was applied to participants. The data collected were analyzed using the Chi-square test and multivariate logistic regression (p<0.05). In the Article 2, the sample will select 124 teeth of children between 5 and 9 years old, of both genders, who present deep caries lesions with pulp involvement and without periapical lesion. The teeth will be divided between Group 1-Mineral Trioxide Aggregate (MTA) and Group 2-Binding of dentin/pulp biostimulation (BBio). Clinical and radiographic analyzes will be performed at 6-and 12-months post treatment. The dentin barrier thickness will be checked using Image J2 software. The chi-square test and t-test were used in the statistical analysis (p<0.05). For Article 1, the results showed that in the total study sample (n=146), 81.51% were female, 52.05% Group 2 and the prevalent age of the interviewees was between 18 and 29 years old (85.62%). Sixty-nine participants

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BiodentineTM versus formocresol pulpotomy technique in primary molars: a 12–month randomized controlled clinical trial

Cited by 44 publications

References 26 publications

Clinical, Radiographical and Histopathological Evaluation of Amniotic Membrane Allograft Pulpotomy in Primary teeth

Clinical, Radiographical and Histopathological Evaluation of Amniotic Membrane Allograft Pulpotomy in Primary teeth

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Alternativas de terapia pulpar vital para reparo do complexo dentino/pulpar de dentes decíduos

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