Bioensaio Para Avaliação Da Atividade Repelente Em Mosquitos Adultos

Nunes, Fabiola da Cruz; Souza, María de Fátima Vanderlei de; Fernandes, Diégina Araújo; Ferreira, Maria Denise Leite; Oliveira, Louise Helena Guimarães de; Figueiredo, Gustavo De; Rique, Gustavo De Figueiredo Hyago Luiz

doi:10.22533/at.ed.8191913119

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“…Of the two tested flavonoids, it was possible to verify that the sulfated flavonoid presents greater repelling power than the glycoside flavonoid. The glycosidic unit in tiliroside may act as an attraction for the insect, considering that in the wild, these mosquitoes feed on plant sap and sugary solutions ( Nunes et al, 2019b ), while the sulfate group (OSO 3 H) may act as an inhibiting agent ( Fernandes et al, 2019 ). This study is the first to show the activity of sulfated flavonoids against adult Ae.…”

Section: Discussionmentioning

confidence: 99%

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Ovicidal, pupicidal, adulticidal, and repellent activity of Helicteres velutina K. Schum against Aedes aegypti L. (Diptera: Culicidae)

et al. 2021

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Aedes aegypti is a vector of emerging and neglected diseases, such as dengue, chikungunya, and Zika. Helicteres velutina, known as "pitó" in Brazil, is traditionally used as an insect repellent, and several studies have demonstrated its larvicidal activity. The aim of this study was to investigate this species and evaluate its potential ovicidal, pupicidal, adulticidal, and repellent activity. The viability of the eggs was evaluated using different concentrations of the test substances for 25 days. The hexane fraction killed 72.7% of the eggs, while dichloromethane killed 67.7%. The survival of the pupae and adults was verified after 72 h and 48 h, respectively. The LC 50 for the hexane and dichloromethane fractions was 0.12 mg/mL and 8.85 mg/mL for pupae, 8.01 mg/mL and 0.74 mg/mL for adults (tarsal test), and 0.05 mg/mL and 0.23 mg/mL for adults (body test), respectively. Repellency was assessed for 240 min using neonatal Wistar rats on a Y-tube olfactometer. The hexane fraction attracted mosquitoes to the test chamber, while the dichloromethane fraction had a repellent action. The 7,4'-di-O-methyl-8-O-sulfate flavone provides greater repellency, and this finding is similar to the results of the in silico studies that have shown the potential of this substance against adult mosquitoes. This suggests that 7,4'-di-O-methyl-8-O-sulfate flavone may be one of the substances present in the extract from aerial parts of H. velutina that is responsible for the repellent activity mentioned in traditional medicine. These findings provide a better understanding of the insecticidal and repellent activity of the extract, fraction, and compounds isolated from H. velutina against Ae. aegypti, thereby revealing its potential in the development of a more effective botanical insecticide.

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Section: Discussionmentioning

confidence: 99%

“…Twenty female mosquitoes, after 24 h of fasting, were placed in the Y-tube olfactometer and observed at an interval of 2 min to record the arm of choice ( Nunes et al, 2019b ). The duration of the repellent activity was evaluated for 4 h at intervals of 0, 30, 120, and 240 min after application ( Rodriguez et al, 2015 ).…”

Section: Methodsmentioning

confidence: 99%