Biofabricated selenium nanoparticles mediated from Goniothalamus wightii gains biomedical applications and photocatalytic degrading ability

Chinnaraj, Santhosh; Balasubramanian, Balamuralikrishnan; Palani, Vino; Maluventhen, Viji; Rejeeth, Chandrababu; Kannan, Soundarapandian; Ullah, Hammad; Rengasamy, Kannan R.R.; Daglia, Maria; Maruthupandian, A.

doi:10.1016/j.jksus.2022.102331

Cited by 9 publications

(7 citation statements)

References 17 publications

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“…XRD analysis was used to examine the bimetallic Se-Ag NPs’ crystal structure and phase. Additionally, Figure 5 a shows the XRD diffraction peaks of selenium nanoparticles, including peaks at 2 θ of the 27.92° (100), 31.8° (101), 47.84° (111), 57.44° (201), 65.64° (210), 76.3° (113), and 84.0° (301) conventional selenium nanoparticle crystal planes, respectively [ 51 ], demonstrating the crystal nature of the synthesized bimetallic Se-Ag NPs with polycrystalline configuration.…”

Section: Resultsmentioning

confidence: 99%

Watermelon Rind Mediated Biosynthesis of Bimetallic Selenium-Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activities

Hashem,

El-Sayyad,

Al-Askar

et al. 2023

Plants

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One of the most hazardous diseases that influences human health globally is microbial infection. Therefore, bimetallic nanoparticles have received much attention for controlling microbial infections in the current decade. In the present study, bimetallic selenium–silver nanoparticles (Se-Ag NPs) were effectively biosynthesized using watermelon rind WR extract through the green technique for the first time. UV-visible spectroscopy, transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDX) methods were used to characterize the produced NPs. The results indicated that the bimetallic Se-Ag NPs had synergistic antimicrobial activity at low concentrations, which helped to reduce the toxicity of Ag NPs after the bimetallic Se-Ag NPs preparation and increase their great potential. Se-Ag NPs with sizes ranging from 18.3 nm to 49.6 nm were detected by TEM. Se-Ag NP surfaces were uniformly visible in the SEM picture. The cytotoxicity of bimetallic Se-Ag NPs was assessed against the Wi38 normal cell line to check their safety, where the IC50 was 168.42 µg/mL. The results showed that bimetallic Se-Ag NPs had antibacterial action against Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella oxytoca, Bacillus subtilis, and Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 12.5 to 50 µg/mL. Additionally, bimetallic Se-Ag NPs had promising anticancer activity toward the MCF7 cancerous cell line, where the IC50 was 21.6 µg/mL. In conclusion, bimetallic Se-Ag NPs were biosynthesized for the first time using WR extract, which had strong antibacterial, antifungal and anticancer properties.

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Section: Resultsmentioning

confidence: 99%

Watermelon Rind Mediated Biosynthesis of Bimetallic Selenium-Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activities

Hashem,

El-Sayyad,

Al-Askar

et al. 2023

Plants

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“…The crystal structure and phase of the bimetallic Se–Au BNPs were also analyzed by XRD. In addition, Figure 1A displays the selenium nanoparticle XRD diffraction peaks, including peaks at 2θ of the 23.82° (100), 30.8° (101), 41.84° (111), 51.44° (201), and 67.34° (210) conventional selenium nanoparticle crystal planes ( Santhosh et al, 2022 ), demonstrating the cubic crystalline structure of the synthesized Se–Au BNPs. Only one undeveloped peak related to P. indica research was observed, at 22.42° (denoted as ©); this research is focused on the production and longevity of Se–Au BNPs.…”

Section: Resultsmentioning

confidence: 99%

Green biosynthesis of bimetallic selenium–gold nanoparticles using Pluchea indica leaves and their biological applications

Aly Khalil,

Saied,

Mekky

et al. 2024

Front. Bioeng. Biotechnol.

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Increasing bacterial resistance and the negative impact of currently used antibacterial agents have produced the need for novel antibacterial agents and anticancer drugs. In this regard, nanotechnology could provide safer and more efficient therapeutic agents. The main methods for nanoparticle production are chemical and physical approaches that are often costly and environmentally unsafe. In the current study, Pluchea indica leaf extract was used for the biosynthesis of bimetallic selenium–gold nanoparticles (Se-Au BNPs) for the first time. Phytochemical examinations revealed that P. indica leaf extract includes 90.25 mg/g dry weight (DW) phenolics, 275.53 mg/g DW flavonoids, and 26.45 mg/g DW tannins. X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared (FTIR) spectroscopy, dynamic light scattering (DLS), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX) techniques were employed to characterize Se-Au BNPs. Based on UV-vis spectra, the absorbance of Se-Au BNPs peaked at 238 and 374 nm. In SEM imaging, Se-Au BNPs emerged as bright particles, and both Au and Se were uniformly distributed throughout the P. indica leaf extract. XRD analysis revealed that the average size of Se-Au BNPs was 45.97 nm. The Se-Au BNPs showed antibacterial properties against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis, with minimum inhibitory concentrations (MICs) of 31.25, 15.62, 31.25, and 3.9 μg/mL, respectively. Surprisingly, a cytotoxicity assay revealed that the IC50 value toward the Wi 38 normal cell line was 116.8 μg/mL, implying that all of the MICs described above could be used safely. More importantly, Se-Au BNPs have shown higher anticancer efficacy against human breast cancer cells (MCF7), with an IC50 value of 13.77 μg/mL. In conclusion, this paper is the first to provide data on the effective utilization of P. indica leaf extract in the biosynthesis of biologically active Se-Au BNPs.

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“…The DPPH free radical assay scavenged by G. wightii extracts in this method described by Santhosh et al (2022) slight modifications. A total 1.98 mg of DPPH dissolved in 25 mL of ethanol and standard also prepared at the same.…”

Section: 2-diphenyl-1-picryl-hydrazyl Assay (Dpph)mentioning

confidence: 99%

“…India has a wide range of traditional medicines based on natural sources of plants to cure numerous diseases and disorders (Santhosh et al, 2022). Herbal medicines play a significant role in health-care initiatives, particularly in developed nations (Sreedhar et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Pharmacognostic, characterization, physio-chemical scrutinizes, and biological attributes of Goniothalamus wightii

Palani,

Balasubramanian,

Chinnaraj

et al. 2023

NRFHH

Self Cite

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To evaluate the quality control parameters of Goniothalamus wightii leaves, which are used for traditional medicine. The leaves extracts were characterized and to evaluate the phytochemical composition, antibacterial, antibiofilm and antioxidant activities. The macroscopic studies of the leaves are simply arranged, green color and dicot plant. The physico-chemical values are the presence of foreign matter, loss on drying, moisture and tannin content, no swelling and foaming capacity. Total ash, acid-insoluble ash, water soluble ash, and sulphated ash are the ash values; extractive values are examined in various organic solvents with visualized UV to exhibit various color variations. The proximate compositions were fiber, soluble and insoluble fiber, carbohydrates, and lipid content presence at g/100g. The quantitative phytoconstituents presence of hexane, ethyl acetate and methanol extracts such as were resolved in sequential extraction with hexane, chloroform, ethyl acetate, and methanol bands were separated. The FT-IR spectrum resembles the aliphatic and aromatic amines, and the LC-MS were identified by phenolic and flavonoids derivatives, steroids, lignin’s. The compounds based the antioxidant activities were 50-80% inhibition against the free radicals and antibacterial, antibiofilm activities were strongly killed the pathogens (E. coli, E. faecalis). In concluded that the pharmacognostic standardization is the first report in these species. The extracts of G. wightiii have potential antioxidant, antibacterial and antibiofilm effects, which could lead to pharmaceutical and industrial applications.

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Biofabricated selenium nanoparticles mediated from Goniothalamus wightii gains biomedical applications and photocatalytic degrading ability

Cited by 9 publications

References 17 publications

Watermelon Rind Mediated Biosynthesis of Bimetallic Selenium-Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activities

Watermelon Rind Mediated Biosynthesis of Bimetallic Selenium-Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activities

Green biosynthesis of bimetallic selenium–gold nanoparticles using Pluchea indica leaves and their biological applications

Pharmacognostic, characterization, physio-chemical scrutinizes, and biological attributes of <i>Goniothalamus wightii</i>

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