Biofiltration and disinfection codetermine the bacterial antibiotic resistome in drinking water: A review and meta-analysis

Wan, Kun; Lin, Wenfang; Zhu, Shuai; Zhang, Shenghua; Yu, Xin

doi:10.1007/s11783-019-1189-1

Cited by 19 publications

(2 citation statements)

References 103 publications

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“…Thus, a large number of disinfectants (chlorine disinfectants, hypochlorous acid, ozone, etc.) have been applied to inactivate SARS-CoV-2 in wastewater. − At present, chlorine disinfectants are most widely used, as free chlorine could effectively inactivate SARS-CoV-2 by destroying the proteins on its envelope . Despite the rapid response around the world, SARS-CoV-2 continues to show a pandemic trend due to the shortage of disinfectants.…”

Section: Water-related Concerns and Strategies For Controlling Corona...mentioning

confidence: 99%

A Global Overview of SARS-CoV-2 in Wastewater: Detection, Treatment, and Prevention

et al. 2021

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A novel coronavirus (SARS-CoV-2) causing corona virus disease 2019 (COVID-19) has attracted global attention due to its highly infectious and pathogenic properties. Most of current studies focus on aerosols released from infected individuals, but the presence of SARS-CoV-2 in wastewater also should be examined. In this review, we used bibliometrics to statistically evaluate the importance of water-related issues in the context of COVID-19. The results show that the levels and transmission possibilities of SARS-CoV-2 in wastewater are the main concerns, followed by potential secondary pollution by the intensive use of disinfectants, sludge disposal, and the personal safety of workers. The presence of SARS-CoV-2 in wastewater requires more attention during the COVID-19 pandemic. Thus, the most effective techniques, i.e., wastewater-based epidemiology and quantitative microbial risk assessment, for virus surveillance in wastewater are systematically analyzed. We further explicitly review and analyze the successful operation of a sewage treatment plant in Huoshenshan Hospital in China as an example and reference for other sewage treatment systems to properly ensure discharge safety and tackle the COVID-19 pandemic. This review offers deeper insight into the prevention and control of SARS-CoV-2 and similar viruses in the post-COVID-19 era from a wastewater perspective.

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Section: Water-related Concerns and Strategies For Controlling Corona...mentioning

confidence: 99%

A Global Overview of SARS-CoV-2 in Wastewater: Detection, Treatment, and Prevention

et al. 2021

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“…Antibiotic resistance genes (ARGs) are emerging environmental pollutants ( Pruden et al, 2006 ). The excessive use and abuse of antibiotics in medicine and agriculture have promoted the emergence, spread, and accumulation of ARGs in various environmental matrices ( Jia et al, 2019 ), including natural and man-impacted environments, such as soil ( Fang et al, 2015 ), sediment ( Jiang et al, 2018 ), surface water ( Zhang et al, 2020b ), wastewater ( Wang et al, 2020 ), groundwater ( Wu et al, 2020 ), drinking water ( Wan et al, 2020 ), and tap water ( Ma et al, 2019 ). Thus, antimicrobial resistance has become a global issue and is regarded as a medical concern by both researchers and the public.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Antibiotic Resistance Genes and Antibiotic-Resistant Bacteria in Full-Scale Drinking Water Treatment System Using Metagenomics and Culturing

Sun

Lin

et al. 2022

Front. Microbiol.

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The contamination of antibiotic resistance genes (ARGs) may directly threaten human health. This study used a metagenomic approach to investigate the ARG profile in a drinking water treatment system (DWTS) in south China. In total, 317 ARG subtypes were detected; specifically, genes encoding bacitracin, multidrug, and sulfonamide were widely detected in the DWTS. Putative ARG hosts included Acidovorax (6.0%), Polynucleobacter (4.3%), Pseudomonas (3.4%), Escherichia (1.7%), and Klebsiella (1.5%) as the enriched biomarkers in the DWTS, which mainly carried bacitracin, beta-lactam, and aminoglycoside ARGs. From a further analysis of ARG-carrying contigs (ACCs), Stenotrophomonas maltophilia and Pseudomonas aeruginosa were the most common pathogens among the 49 ACC pathogens in the DWTS. The metagenomic binning results demonstrated that 33 high-quality metagenome-assembled genomes (MAGs) were discovered in the DWTS; particularly, the MAG identified as S. maltophilia-like (bin.195) harbored the greatest number of ARG subtypes (n = 8), namely, multidrug (n = 6; smeD, semE, multidrug_transporter, mexE, semB, and smeC), beta-lactam (n = 1; metallo-beta-lactamase), and aminoglycoside [n = 1; aph(3’)-IIb]. The strong positive correlation between MGEs and ARG subtypes revealed a high ARG dissemination risk in the DWTS. Based on the pure-culture method, 93 isolates that belong to 30 genera were recovered from the DWTS. Specifically, multidrug-resistant pathogens and opportunistic pathogens such as P. aeruginosa, Bacillus cereus, and S. maltophilia were detected in the DWTS. These insights into the DWTS’s antibiotic resistome indicated the need for more comprehensive ARG monitoring and management in the DWTS. Furthermore, more effective disinfection methods need to be developed to remove ARGs in DWTSs, and these findings could assist governing bodies in the surveillance of antibiotic resistance in DWTSs.

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Occurrence and Health Risks of Antibiotic Resistance in African Aquatic Systems

Gwenzi

Ngaza

Marumure

et al. 2023

Antimicrobial Research and One Health in Africa

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Biofiltration and disinfection codetermine the bacterial antibiotic resistome in drinking water: A review and meta-analysis

Cited by 19 publications

References 103 publications

A Global Overview of SARS-CoV-2 in Wastewater: Detection, Treatment, and Prevention

A Global Overview of SARS-CoV-2 in Wastewater: Detection, Treatment, and Prevention

Characteristics of Antibiotic Resistance Genes and Antibiotic-Resistant Bacteria in Full-Scale Drinking Water Treatment System Using Metagenomics and Culturing

Occurrence and Health Risks of Antibiotic Resistance in African Aquatic Systems

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