Biogenic green synthesis of metal oxide nanoparticles using oat biomass for ultrasensitive modified polymeric sensors

Abstract

This study describes Green synthesis of two metal oxide nanoparticles MnO 2 NPs and CuONPs using the oat biomass. The electrocatalytic activity of the synthesized metal oxide nanoparticles was investigated by fabricating two modified sensors enriched with MnO 2 NPs and CuONPs as a coated layer on the surface of the sensors and utilized to quantify antibacterial drugs cephalexin (CPX) and cefazolin (CFZ) in their commercial products and biosamples. The tested drugs were incorporated with the precipitating agents phosphomolybdic acid and phosphotungstic acid to form CPX-PM and CFZ-PT as electroactive materials, respectively. Conductivity enhancement of the fabricated modified sensors CPX-PM-MnO 2 NPs and CFZ-PT-CuONPs was determined and the outcomes compared to the results obtained from the conventional types of the same sensors. Linear relationships were recorded between the sensory potentials of the enriched metal oxide nanoparticles in the ranges of 1.0 × 10-8-1.0 × 10-2 and 1.0 × 10-10-1.0 × 10-2 mol L-1 with lower limits of detection 5.6 × 10-9 and 5.7 × 10-11 mol L-1 for CPX-PM-MnO 2 NPs and CFZ-PT-CuONPs with respect to 1.0 × 10-6-1.0 × 10-2 mol L-1 of their conventional coated wire types. The fabricated sensors provide excellent sensitivity and selectivity towards the determination of CPX and CFZ in its commercial and biosamples.

Highly Functionalized Modified Metal Oxides Polymeric Sensors for Potentiometric Determination of Letrozole in Commercial Oral Tablets and Biosamples

“…In the current study, o -NPOE acted as a fluidizer aiding homogenous dissolution of ion-pair and permitting its diffusion mobility inside the membrane. The elevated dielectric constant of o -NPOE (ε = 24) improves membrane selectivity towards the tested analyte by influencing the dissolution of ion pair within the active membrane and consequently increase its partition coefficient and gave suitable mechanical feature [ 48 ].…”

Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications

“…These biomolecules, in addition to the abovedescribed medicinal properties, exhibit antimicrobial and antioxidant activities [30,31]. Besides, the phytochemical profile of oat biomass includes natural chemical components which have been employed for the biosynthesis of nanomaterials such as metal and metal oxide nanoparticles [32,33]. Additionally, one of the major environmental hazards is the effluent from the dyeing and pigment industries, which possess various toxic and nonbiodegradable by-products [34].…”

New Construction of Functionalized CuO/Al2O3 Nanocomposite-Based Polymeric Sensor for Potentiometric Estimation of Naltrexone Hydrochloride in Commercial Formulations

“…The potentiometric coated wire sensors are commonly constructed from highly conductive metal wire such as silver, gold, platinum, copper and aluminium. The metal wire is used as a substrate which is coated with a polymeric cocktail containing the active sites of the selective membrane [42]. Sodium tetraphenylborate (Na-TPB) is a white powder that has the ability to catalyze the ion-exchange process via the interfaces of hydrophobic membrane when used with a suitable ion-pair complex [43].…”