Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products

Abstract

Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs have several advantages over chemically synthesized ones due to their eco-friendly synthesis regimen, sustainability, biocompatibility, and diverse multifarious biomedical applications. Moreover, the superior cytocompatibility and stability due to the capping layer over metallic nanoparticles (MNPs), reduces the like hood of toxicity and side effects, making them a safer alternative to traditional drug delivery methods. Among several promising applications of BMNPs, their antibacterial activity, analytical sensing of heavy metals, and their roles in food preservations have been widely explored. In addition, to drug delivery and imaging, BMNPs have also been investigated for therapeutic activity such as antimicrobial efficacy against the skin and soft tissue nosocomial pathogens and targeting cancer cells in cancer therapy. The present review bestows several characterization techniques involved with MNPs and compressive aspects of the biogenic synthesis of MNPs using agricultural and biological materials, which reduces the cost of synthesis and minimizes the use of hazardous chemicals. The review also focuses on the multifold applications of BMNPs including biomedical, analytical, preservation of food, and in other consumable goods with toxicological aspects.

Syzygium aromaticum Bud Extracted Core–Shell Ag–Fe Bimetallic Nanoparticles: Phytotoxic, Antioxidant, Insecticidal, and Antibacterial Properties

“…The attraction of BMNPs toward the chip showed magnetic characteristics and confirmed the core-shell structure of BMNPs. A similar experiment was performed by Sher et al in 2021 [62].…”

Emerging Trends of Nanomedicines in the Management of Prostate Cancer: Perspectives and Potential Applications

“…They have been shown to make drugs less dangerous, concentrate drugs at disease sites, keep them in the body longer, protect them in the body, protect them the body, and protect drugs from humoral attacks [ 67 ]. Nanoparticles like metal nanomaterials [ 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 ], porous silicon nanoparticles, and liposomes [ 79 , 80 , 81 ] have been studied extensively to see how they can treat prostate cancer. Active targeting nanoparticles contain peptides, oligosaccharides, antibodies, or other molecules that have modified surfaces.…”

Electrospun Nanofiber Scaffolds Loaded with Metal-Based Nanoparticles for Wound Healing

“…3. Once inside the cell, MBNPs are free to interact with cellular structures (e.g., membranes, ribosomes, proteins, DNA, RNA), disrupting cell functions [ 65 , 66 ]. Moreover, some metal-based nanoparticles can directly promote angiogenesis, ECM accumulation, or wound re-epithelialization through their own functions (such as anti-inflammatory, antioxidant, cell proliferation-promoting, and cytokine-regulating effects), or through combining MBNPs with photothermal therapy (PTT) and photodynamic therapy (PDT).…”