Biogenic silver and silver oxide hybrid nanoparticles: a potential antimicrobial against multi drug-resistant <i>Pseudomonas aeruginosa</i>

D’Lima, Lynn; Phadke, Manju; Ashok, Vishal Dev

doi:10.1039/c9nj04216d

Cited by 31 publications

(31 citation statements)

References 17 publications

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“…D’Lima et al reported Ag/Ag 2 O NPs by employing a biosynthesis approach using a novel strain of Kitasatospora albolonga . 316 The microscopic and structural analysis of obtained material reveals a spherical shaped Ag–Ag 2 O hybrid core–shell (Ag 2 O@Ag) structured NPs ( Figure 14 a). Though these hybrid NPs had shown antimicrobial activity independently, however, when combined with carbenicillin, it showed an improved toxic synergetic effect on multi-drug-resistant P. aeruginosa (MDRP) at low concentrations ( Figure 14 b).…”

Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

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Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

213

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The ongoing worldwide pandemic due to COVID-19 has created awareness toward ensuring best practices to avoid the spread of microorganisms. In this regard, the research on creating a surface which destroys or inhibits the adherence of microbial/viral entities has gained renewed interest. Although many research reports are available on the antibacterial materials or coatings, there is a relatively small amount of data available on the use of antiviral materials. However, with more research geared toward this area, new information is being added to the literature every day. The combination of antibacterial and antiviral chemical entities represents a potentially path-breaking intervention to mitigate the spread of disease-causing agents. In this review, we have surveyed antibacterial and antiviral materials of various classes such as small-molecule organics, synthetic and biodegradable polymers, silver, TiO2, and copper-derived chemicals. The surface protection mechanisms of the materials against the pathogen colonies are discussed in detail, which highlights the key differences that could determine the parameters that would govern the future development of advanced antibacterial and antiviral materials and surfaces.

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Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

213

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“…AgNPs were shown to have antimicrobial properties against several pathogenic microorganisms ( Scandorieiro et al., 2016 ; Figueiredo et al., 2019 ), including Pseudomonas aeruginosa ( Liao et al., 2019 ; D’Lima et al., 2020 ). This bacterium can be found in various environments, such as hospitals, natural resources, and water supply systems ( Dobias and Bernier-Latmani, 2013 ; Anversa et al., 2019 ; Esmaeili et al., 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Subinhibitory Concentrations of Biogenic Silver Nanoparticles Affect Motility and Biofilm Formation in Pseudomonas aeruginosa

Saeki¹,

Yamada²,

Araujo³

et al. 2021

Front. Cell. Infect. Microbiol.

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Biogenic silver nanoparticles (bio-AgNPs) are increasingly recognized as an antibiofilm and antivirulence strategy against P. aeruginosa, a bacterium that causes chronic infections in immunocompromised and cystic fibrosis patients. This study aimed to investigate the effects of subinhibitory concentrations of bio-AgNPs on motility and biofilm formation in P. aeruginosa. Bio-AgNPs were synthesized via reduction of ionic silver catalyzed by cell-free culture filtrate from Fusarium oxysporum. A total of 17 P. aeruginosa isolates and strains were evaluated for swarming, swimming, and twitching motility in the presence and absence (control) of bio-AgNPs, including 10 clinical isolates from patients with and without cystic fibrosis, 5 environmental isolates obtained from the public water supply system, and 2 reference strains (PAO1 and PA14). Isolates were identified by biochemical and molecular methods. Minimum inhibitory concentrations (MICs) were determined by the broth microdilution method. Swarming, swimming, and twitching motility assays were performed in Petri dishes. Biofilm formation capacity was assessed quantitatively by the crystal violet method. MIC values ranged from 15.62 to 62.50 µM. The results showed that subinhibitory concentrations of bio-AgNPs (½ MIC, 7.81–31.25 µM) significantly increased (p < 0.05) swarming, swimming, and twitching motility in 40.0, 40.0, and 46.7% of isolates, respectively. Subinhibitory bio-AgNP treatment enhanced (p < 0.05) biofilm formation capacity in PA14 and a cystic fibrosis isolate (P11). It is concluded that subinhibitory concentrations of bio-AgNPs increased biofilm formation and swarming, swimming, and twitching motility in PA14 and some P. aeruginosa isolates. These virulence factors are directly involved with quorum-sensing systems. Further research should investigate the effects of AgNPs on P. aeruginosa quorum sensing to help elucidate their mechanism of action at subinhibitory concentrations.

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“…[ 60 ] Although silver oxide NPs have not yet been tested against viruses, they are promising antiviral candidates owing to their known antimicrobial activity. [ 230–232 ] Furthermore, Minoshima et al. demonstrated the efficacy of Cu 2 O particles (0.5–5 µm) and silver ionic compounds (AgNO 3 and Ag 2 O) against the H1N1 influenza virus with the denaturation of viral receptor proteins, such as hemagglutinin (HA).…”

Section: Ceramics Against Virusesmentioning

confidence: 99%

From Bulk to Nanoparticles: An Overview of Antiviral Materials, Its Mechanisms, and Applications

Rodrigues

Campo

Arns

et al. 2021

Part & Part Syst Charact

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Infectious diseases caused by viruses are a global health concern and have become prominent in light of the recent COVID‐19 pandemic. Considering the limitations of drugs and prophylactic methods used in current medicine, antiviral materials are a useful strategy in preventing the spread of viruses and enhancing treatment efficiency. Thus, this review highlights the state‐of‐the‐art antiviral materials, describes the scientific landscape of the primary antiviral materials used based on bibliometric analysis, presents their mechanisms of action, and discusses their clinical applications. The mechanisms of action underlying the broad‐spectrum antiviral properties of metals, ceramics, polymers, and composites are also discussed. Polyanions, polycations, oxides, and metal‐based materials, from bulk to nanoparticles, have good potential in antiviral applications that may help prepare the world for future viral breakouts.

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Biogenic silver and silver oxide hybrid nanoparticles: a potential antimicrobial against multi drug-resistant Pseudomonas aeruginosa

Abstract: Ag/Ag2O NPs synthesized using K. abolonga exhibited antimicrobial activity along with carbenicillin against MDR P. aeruginosa.

Cited by 31 publications

References 17 publications

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Subinhibitory Concentrations of Biogenic Silver Nanoparticles Affect Motility and Biofilm Formation in Pseudomonas aeruginosa

From Bulk to Nanoparticles: An Overview of Antiviral Materials, Its Mechanisms, and Applications

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