Biogenic Silver Nanoparticles from Iris tuberosa as Potential Preservative in Cosmetic Products

Abstract

Biogenic-silver nanoparticles emerge as new nanosilver platforms that allow us to obtain silver nanoparticles via “green chemistry”. In our study, biogenic-silver nanoparticles were obtained from Iris tuberosa leaf extract. Nanoparticles were characterized by a UV-vis spectroscopy, dynamical light scattering technique. The transmission electron microscope revealed spheric and irregular nanoparticles with 5 to 50 nm in diameter. Antimicrobial properties were evaluated against typical microbial contaminants found in cosmetic products, showing high antimicrobial properties. Furthermore, natural moisturizing cream was formulated with biogenic-silver nanoparticles to evaluate the preservative efficiency through a challenge test, indicating its promising use as preservative in cosmetics.

Green Synthesis of Silver Nanoparticles Using Natural Extracts with Proven Antioxidant Activity

“…More recently, the usefulness of Cannabis sativa leaf extracts to mediate the green synthesis of AgNPs and their antibacterial activity against several human pathogens ( Escherichia coli , Klebsiella pneumoniae , Pseudomonas fluorescens , and Staphylococcus aureus ) have been proven [ 26 ]. An interesting application of plant-mediated AgNPs was demonstrated by Mondéjar-López et al [ 27 ]. The authors obtained AgNPs by the use of Iris tuberosa leaf extract.…”

Thymoquinone-Loaded Chitosan Nanoparticles as Natural Preservative Agent in Cosmetic Products

“…These results confirm the preservative activity of NPCH-TQ in formulated creams. Other works with biogenic silver nanoparticles from Iris tuberosa aqueous extract confirm the role of nanotechnology to be used as a platform to obtain new preservative agents [5].…”

“…This delocalization also causes an intensification in the purplish color characteristic of the radical, which in an ethanolic medium absorbs at 515 nm. This purplish coloration of the solution is attenuated in the presence of an antioxidant that can donate or transfer a hydrogen atom, giving a yellowish color due to the reduced form of DPHP-H [5]. Figure 3 presents the % of DPPH scavenging of free TQ, NPCH and NPCH-TQ on the range of concentrations between 0.125 and 1 of tested material.…”

“…FRS, free radical scavenging activity, was determined as described previously [5]. Briefly, 0.5 mL for each concentration (1 mg/mL, 500 µg/mL, 250 µg/mL, and 125 µg/mL) of synthetized NPCH-CAR, NPCH-EUG, and free terpenes was mixed with 0.1 mM ethanolic DPPH radical solution (1.5 mL) and then mixed and kept in the dark at room temperature for 30 min.…”

“…One of the most common approaches is the incorporation of preservative agents, i.e., substances that inhibit the growth of microorganisms and counteract the generation of reactive oxygen species and oxidation processes [4]. Some cosmetic preservatives such as parabens, triclosan, benzalkonium chloride, formaldehyde, phenoxyethanol, and chlorphenesin produce adverse effects in humans such as DNA damage, antiandrogenic activity, cytotoxicity and genotoxic effects on human lymphocytes, cytotoxicity in meibomian glands, risk of cancer, and allergic reactions and also produce environmental and animal toxicity [5,6]. Due to these results, the traditional use of preservatives in cosmetics is leading us to search for new "eco-friendly" and efficient alternatives.…”