Biogenic silver nanoparticles using Oxalis corniculata characterization and their clinical implications

Karimzadeh, Katayoon; sharifi, Elham; Bakhshi, Nahid; Ramzanpoor, Mahdieyeh

doi:10.1016/j.jddst.2019.101263

Cited by 16 publications

(14 citation statements)

References 46 publications

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“…[16][17][18]. Three terpenes were reported in this study; (E)-phytol is not detected this time in O. corniculata but was previously isolated by Aruna et al [8] and Karimzadeh et al [7], limonene and linalylanthranilate were identified for the first time in Oxalis species; the former was previously separated from Averrhoa bilimbi L. (oxalidaceae) [19] while the latter was reported before from family lamiaceae Martinov [20,21]. All carboxylic acid esters in the present study were not isolated before from genus Oxalis or even from the family but were identified from other families such as Acanthaceae Juss., Rosaceae Juss., Apiaceae Lindl.…”

Section: Gc-ms Analysismentioning

confidence: 63%

“…The data concerning isolation and identification of non-polar and volatile constituents from Oxalis species are limited. Only Karimzadeh et al [7], Aruna et al [8], Durgawale et al [9] and Unni et al [10] reported the chemical profile of O. corniculata using GC-MS technique and there were not any previous investigations for detecting the nonpolar constituents from the other species of the present study. Some members of genus Oxalis has multiple therapeutic effects and used traditionally for treating various diseases such as O. corniculata which used as anti-diabetic, anti-microbial, antioxidant and hepatoprotective [7][8][9][10].…”

Section: Introductionmentioning

confidence: 62%

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Comparative study of Oxalis L. species growing wild in Egypt: GC-MS analysis and chemosystematic significance

et al. 2021

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Five Oxalis L. plants belonging to three different sections were collected and subjected to GC-MS analysis to evaluate and understand the relationship between them from the chemosystematic point of view. The GC-MS analysis revealed the identification and characterization of thirty seven compounds belonging to different non-polar chemical classes of which nine compounds (two aliphatic hydrocarbons, one diterpene, one fatty acid, four fatty acid esters and one fatty alcohol) were identified before from the genus while, the rest compounds were identified for the first time. The GC-MS results were chemosystematically significant among Oxalis species and were found to be a good parameter in finding a tangible demarcation between O. corniculata and O. corniculata var. repens, on the other hand it is difficult to differentiate between Oxalis sections by the obtained data.

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Section: Gc-ms Analysismentioning

confidence: 63%

Section: Introductionmentioning

confidence: 62%

Comparative study of Oxalis L. species growing wild in Egypt: GC-MS analysis and chemosystematic significance

et al. 2021

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“…However, the anticancer targets of these medicinal compounds are unknown, which is the major challenge in the development of Chinese herbal biomedical applications. The aqueous extract of Oxalis corniculata synthesized AgNPs with potential cytotoxic activity against colon cancer HT29 cells [ 177 ]. Moreover, these findings indicate that O. corniculata is a highly efficient reducing agent with potential biomedical applications.…”

Section: Further Biomedical Applications Of Chinese Herb-synthesized Agnpsmentioning

confidence: 99%

Biomedical Applications of Chinese Herb-Synthesized Silver Nanoparticles by Phytonanotechnology

2021

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Recent advances in nanotechnology have opened up new avenues for the controlled synthesis of nanoparticles for biomedical and pharmaceutical applications. Chinese herbal medicine is a natural gift to humanity, and it has long been used as an antibacterial and anticancer agent. This study will highlight recent developments in the phytonanotechnological synthesis of Chinese herbal medicines to utilize their bioactive components in biomedical and therapeutic applications. Biologically synthesized silver nanoparticles (AgNPs) have emerged as a promising alternative to chemical and physical approaches for various biomedical applications. The comprehensive rationale of combinational or synergistic effects of Chinese herb-based AgNPs synthesis was investigated with superior physicochemical and biological properties, and their biomedical applications, including antimicrobial and anticancer activity and wound healing properties. AgNPs can damage the cell ultrastructure by triggering apoptosis, which includes the formation of reactive oxygen species (ROS), DNA disintegration, protein inactivation, and the regulation of various signaling pathways. However, the anticancer mechanism of Chinese herbal medicine-based AgNPs is more complicated due to the potential toxicity of AgNPs. Further in-depth studies are required to address Chinese herbs’ various bioactive components and AgNPs as a synergistic approach to combat antimicrobial resistance, therapeutic efficiency of drug delivery, and control and prevention of newly emerged diseases.

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“…Several studies have been carried out on using naturally occurring compounds as anticancer agents in relation to appropriate antioxidant activity ( 6 ).…”

Section: Introductionmentioning

confidence: 99%

“…In general, the seaweeds consist of three phyla, namely green, red, and brown algae, and three families, including Chlorophyceae , Rhodophyceae , and Phaeophyceae . The red algae or Rhodophyceae are major algae groups in bioactive compounds ( 6 ). Moussavou et al .…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening, antioxidant potential, and cytotoxic effects of different extracts of red algae (Laurencia snyderiae) on HT29 cells

Karimzadeh

Zahmatkesh

2021

Research in Pharmaceutical Sciences

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Background and purpose: Marine algae are potential renewable and sustainable sources of bioactive natural products which can be utilized in nutraceutical and pharmaceutical industries. Experimental approach: Different extracts (methanol, chloroform, and ethyl acetate) of red algae, Laurencia snyderiae , was evaluated for their antioxidant potential, with various antioxidant assessment assays, cytotoxic properties (using MTT colorimetric assay), and phytochemical constituents (total phenolic and flavonoid contents). The GC-MS analyses of the algal methanolic extract and its apoptotic effects on the human colon carcinoma cell line (HT29) were also investigated. Findings/Results: The total phenolic content in the methanol, chloroform, and ethyl acetate extracts of L. snyderiae was 3.6 ± 0.12, 3.2 ± 0.41, and 3.3 ± 0.35 μg/mg of gallic acid, respectively. Among different algae extracts, chloroform extract showed significantly chelating ability (IC 50 = 0.027 mg/mL) and reducing power activity (IC 50 = 0.082 mg/mL), while the highest DPPH scavenging activity (IC 50 = 0.058 mg/mL) exhibited in the methanol extract compared to the other extracts. The methanolic extract was found to have a higher cytotoxicity effect on colon carcinoma cells with IC 50 70.2 μg/mL. The viability of the cancer cells was increased with the decrease in the concentration in different extracts. GC-MS analysis of the algal methanolic extract revealed the presence of active antitumor constituents and apoptosis-based cytotoxicity against colon cancer cells through the DNA damage was also confirmed. Conclusion and implications: Based on these results, the red algae L. snyderiae possesses potent bioactive constituents and can use as additional resources as a natural antioxidant and antitumor agent in the pharmaceutical and nutraceutical area.

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Biogenic silver nanoparticles using Oxalis corniculata characterization and their clinical implications

Cited by 16 publications

References 46 publications

Comparative study of Oxalis L. species growing wild in Egypt: GC-MS analysis and chemosystematic significance

Comparative study of Oxalis L. species growing wild in Egypt: GC-MS analysis and chemosystematic significance

Biomedical Applications of Chinese Herb-Synthesized Silver Nanoparticles by Phytonanotechnology

Phytochemical screening, antioxidant potential, and cytotoxic effects of different extracts of red algae (Laurencia snyderiae) on HT29 cells

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